HitPredict

Interactor 1: ISG15 (P05161)
Ubiquitin-like protein ISG15 (Interferon-induced 15 kDa protein) (Interferon-induced 17 kDa protein) (IP17) (Ubiquitin cross-reactive protein) (hUCRP)
Gene: ISG15

Interactor 2: SYEP (P07814)
Bifunctional glutamate/proline--tRNA ligase (Bifunctional aminoacyl-tRNA synthetase) (Cell proliferation-inducing gene 32 protein) (Glutamatyl-prolyl-tRNA synthetase) [Includes: Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS); Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase)]
Gene: EPRS1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33024031
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 165 Hs			1 1512
+	Hs
		430919 RL40_HUMAN (3-82): 1.77e-34: 119: 27.50		SYEP_HUMAN (1-1512): 0: 1810: 100.00
+	At
		287592 UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55		SYEC_ARATH (1-709): 0: 773: 41.35
+	At
		96153 UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55		F4ICG2_ARATH (146-706): 0: 591: 30.65
+	Hs
		397836 ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00		SYQ_HUMAN (159-704): 0: 631: 31.19
+	Hs
		397792 ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00		SYTC_HUMAN (703-1410): 0: 573: 15.62
+	At
		1092089 UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55		SYPM_ARATH (995-1512): 1.98e-147: 463: 37.00
+	Hs
		475343 UBC_HUMAN (3-157): 5.42e-62: 203: 32.26		SYWC_HUMAN (751-804): 5.49e-09: 62.4: 51.72
+	Hs
		397779 ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00		SYWC_HUMAN (751-804): 5.49e-09: 62.4: 51.72
+	Rn
		1144209 UBC_RAT (2-110): 2.29e-33: 125: 28.44		SYWC_RAT (813-911): 7.04e-10: 65.5: 41.67