HitPredict

Interactor 1: ISG15 (P05161)
Ubiquitin-like protein ISG15 (Interferon-induced 15 kDa protein) (Interferon-induced 17 kDa protein) (IP17) (Ubiquitin cross-reactive protein) (hUCRP)
Gene: ISG15

Interactor 2: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Species: Homo sapiens

Source: innatedb

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	33024031, 16009940
Identification Methods	affinity chromatography technology, unspecified method
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 165 Hs			1 724
+	Hs
		437828 UBC_HUMAN (3-157): 5.42e-62: 203: 32.26		HS90B_HUMAN (1-724): 0: 1086: 100.00
+	Hs
		397727 ISG15_HUMAN (1-165): 2.83e-48: 155: 100.00		HS90A_HUMAN (1-724): 0: 1072: 85.25
+	Rn
		709239 UBC_RAT (2-110): 2.29e-33: 125: 28.44		HS90B_RAT (1-724): 0: 1089: 99.59
+	At
		137803 UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55		HS904_ARATH (10-724): 0: 1007: 66.85
+	At
		878277 UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55		HS902_ARATH (10-724): 0: 1003: 66.85
+	At
		850795 UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55		HS903_ARATH (10-724): 0: 1002: 66.57
+	At
		646587 UBQ3_ARATH (3-157): 2.86e-64: 200: 33.55		HS901_ARATH (10-724): 0: 999: 67.97
+	Hs
		431722 RL40_HUMAN (3-82): 1.77e-34: 119: 27.50		HS90A_HUMAN (1-724): 0: 1072: 85.25
+	Rn
		924260 RL40_RAT (3-82): 1.77e-34: 119: 27.50		HS90A_RAT (1-724): 0: 1070: 84.45
+	Sc
		365633 UBI4P_YEAST (3-157): 4.74e-62: 197: 32.26		HSP82_YEAST (12-724): 0: 927: 61.26
+	Sc
		477100 UBI4P_YEAST (3-157): 4.74e-62: 197: 32.26		HSC82_YEAST (13-724): 0: 922: 60.22