Interactor 1: CP1A2 (P05177)
Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2) (Cholesterol 25-hydroxylase) (Cytochrome P(3)450) (Cytochrome P450 4) (Cytochrome P450-P3) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152)
Gene: CYP1A2

Interactor 2: CP1A2 (P05177)
Cytochrome P450 1A2 (EC 1.14.14.1) (CYPIA2) (Cholesterol 25-hydroxylase) (Cytochrome P(3)450) (Cytochrome P450 4) (Cytochrome P450-P3) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152)
Gene: CYP1A2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 22738171
Identification Methods fluorescent resonance energy transfer
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains p450~p450
Common GO terms GO:0004497 - monooxygenase activity
GO:0004508 - steroid 17-alpha-monooxygenase activity
GO:0005506 - iron ion binding
GO:0005789 - endoplasmic reticulum membrane
GO:0006706 - steroid catabolic process
and 37 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 516
Hs

1 516
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Oc
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024