HitPredict

Interactor 1: HMGN2 (P05204)
Non-histone chromosomal protein HMG-17 (High mobility group nucleosome-binding domain-containing protein 2)
Gene: HMGN2

Interactor 2: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0005634 - nucleus GO:0061844 - antimicrobial humoral immune response mediated by antimicrobial peptide
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 90 Hs			1 126
+	Hs
		398891 HMGN2_HUMAN (1-90): 3.72e-31: 106: 100.00		H2B2F_HUMAN (1-126): 2.34e-54: 168: 97.62
+	Hs
		398806 HMGN2_HUMAN (1-90): 3.72e-31: 106: 100.00		H2B1J_HUMAN (1-126): 7.8e-54: 166: 99.21
+	Hs
		398845 HMGN2_HUMAN (1-90): 3.72e-31: 106: 100.00		H2BFS_HUMAN (1-126): 1.26e-53: 166: 96.83
+	Hs
		398853 HMGN2_HUMAN (1-90): 3.72e-31: 106: 100.00		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		398924 HMGN2_HUMAN (1-90): 3.72e-31: 106: 100.00		H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41
+	Hs
		241415 HMGN2_HUMAN (1-90): 3.72e-31: 106: 100.00		H2B1K_HUMAN (1-126): 1.56e-53: 165: 98.41
+	Hs
		398846 HMGN2_HUMAN (1-90): 3.72e-31: 106: 100.00		H2B1D_HUMAN (1-126): 3.5e-53: 164: 98.41
+	Hs
		398939 HMGN2_HUMAN (1-90): 3.72e-31: 106: 100.00		H2B1L_HUMAN (1-126): 2.49e-52: 162: 97.62
+	Hs
		398925 HMGN2_HUMAN (1-90): 3.72e-31: 106: 100.00		H2B1A_HUMAN (1-126): 3.43e-46: 147: 85.04
+	Hs
		130216 HMGN4_HUMAN (1-90): 7.94e-22: 82.9: 86.67		H2B1J_HUMAN (1-126): 7.8e-54: 166: 99.21
+	Hs
		130205 HMGN4_HUMAN (1-90): 7.94e-22: 82.9: 86.67		H2B1K_HUMAN (1-126): 1.56e-53: 165: 98.41