Protein: CYC
Cytochrome c

Gene: CYC, CYCS
Organism: Homo sapiens
Interactions: 188
UniProt ID: P99999

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005758 - mitochondrial intermembrane space
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

152870

APAF
Apoptotic protease-activating factor 1

3

0

Small-scale

0.803

High

958530

BRWD1
Bromodomain and WD repeat-containing protein 1

1

1

High-throughput

0.665

High

958506

COX42
Cytochrome c oxidase subunit 4 isoform 2, mitochondrial

4

0

Small-scale

0.659

High

441109

CY1
Cytochrome c1, heme protein, mitochondrial

1

1

Small-scale

0.647

High

958463

K1C40
Keratin, type I cytoskeletal 40

2

0

High-throughput

0.626

High

325134

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

1

High-throughput

0.618

High

473436

UCRIL
Putative cytochrome b-c1 complex subunit Rieske-like protein 1

1

1

High-throughput

0.618

High

958509

PHB2
Prohibitin-2

2

1

High-throughput

0.601

High

625360

CDK2
Cyclin-dependent kinase 2

2

0

High-throughput

0.585

High

958458

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

2

High-throughput

0.571

High

346530

MYC
Myc proto-oncogene protein

2

0

High-throughput

0.559

High

680438

TIA1
Cytotoxic granule associated RNA binding protein TIA1

2

0

Small-scale

0.559

High

2018

A0A0A0MR05
Target of rapamycin complex subunit LST8

1

0

High-throughput

0.556

High

925195

RAC1
Ras-related C3 botulinum toxin substrate 1

2

0

High-throughput

0.547

High

958474

CUL9
Cullin-9

1

0

Small-scale

0.537

High

170334

TIF1A
Transcription intermediary factor 1-alpha

1

1

High-throughput

0.536

High

201302

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

1

High-throughput

0.536

High

334356

AL1A1
Aldehyde dehydrogenase 1A1

1

1

High-throughput

0.536

High

496852

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.536

High

596742

CD11B
Cyclin-dependent kinase 11B

1

1

High-throughput

0.536

High

613415

SFPQ
Splicing factor, proline- and glutamine-rich

1

1

High-throughput

0.536

High

814367

AL1A3
Retinaldehyde dehydrogenase 3

1

1

High-throughput

0.536

High

820887

PRC2A
Protein PRRC2A

1

1

High-throughput

0.536

High

958440

RBL2
Retinoblastoma-like protein 2

1

1

High-throughput

0.536

High

958442

SFSWA
Splicing factor, suppressor of white-apricot homolog

1

1

High-throughput

0.536

High

958483

RB15B
Putative RNA-binding protein 15B

1

1

High-throughput

0.536

High

958490

PHF3
PHD finger protein 3

1

2

High-throughput

0.536

High

958502

RBM33
RNA-binding protein 33

1

2

High-throughput

0.536

High

958514

DIDO1
Death-inducer obliterator 1

1

3

High-throughput

0.536

High

958519

NSRP1
Nuclear speckle splicing regulatory protein 1

1

2

High-throughput

0.536

High

958535

CDK12
Cyclin-dependent kinase 12

1

2

High-throughput

0.536

High

958537

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

1

High-throughput

0.536

High

958543

ZO2
Tight junction protein ZO-2

1

1

High-throughput

0.536

High

958552

CBPC1
Cytosolic carboxypeptidase 1

1

0

High-throughput

0.518

High

718758

PHB1
Prohibitin 1

1

1

High-throughput

0.515

High

958464

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.515

High

590161

CCNA2
Cyclin-A2

1

0

High-throughput

0.513

High

864213

CCHL
Holocytochrome c-type synthase

1

0

High-throughput

0.513

High

958438

KPCZ
Protein kinase C zeta type

1

0

High-throughput

0.513

High

958441

FP100
Fanconi anemia core complex-associated protein 100

1

0

High-throughput

0.513

High

958443

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

0

High-throughput

0.513

High

958457

HABP4
Intracellular hyaluronan-binding protein 4

1

0

High-throughput

0.513

High

958470

DDX46
Probable ATP-dependent RNA helicase DDX46

1

0

High-throughput

0.513

High

958472

LYRIC
Protein LYRIC

1

0

High-throughput

0.513

High

958479

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

1

0

High-throughput

0.513

High

958481

PR38A
Pre-mRNA-splicing factor 38A

1

0

High-throughput

0.513

High

958482

FANCB
Fanconi anemia group B protein

1

0

High-throughput

0.513

High

958484

RP9
Retinitis pigmentosa 9 protein

1

0

High-throughput

0.513

High

958485

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.513

High

958488

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

1

0

High-throughput

0.513

High

958491

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

0

High-throughput

0.513

High

958500

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

0

High-throughput

0.513

High

958505

RSRC1
Serine/Arginine-related protein 53

1

0

High-throughput

0.513

High

958515

DCNL5
DCN1-like protein 5

1

0

High-throughput

0.513

High

958524

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.513

High

958528

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.513

High

958532

FANCL
E3 ubiquitin-protein ligase FANCL

1

0

High-throughput

0.513

High

958533

ARGL1
Arginine and glutamate-rich protein 1

1

0

High-throughput

0.513

High

958534

CWC25
Pre-mRNA-splicing factor CWC25 homolog

1

0

High-throughput

0.513

High

958538

RBM27
RNA-binding protein 27

1

0

High-throughput

0.513

High

958550

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.513

High

958551

ZC3H4
Zinc finger CCCH domain-containing protein 4

1

0

High-throughput

0.513

High

958469

UBP53
Inactive ubiquitin carboxyl-terminal hydrolase 53

1

1

Small-scale

0.512

High

333527

CYB5
Cytochrome b5

1

1

Small-scale

0.501

High

560189

NCPR
NADPH--cytochrome P450 reductase

1

1

Small-scale

0.501

High

682330

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

2

Small-scale

0.501

High

958547

NDOR1
NADPH-dependent diflavin oxidoreductase 1

1

1

Small-scale

0.501

High

958553

GSTK1
Glutathione S-transferase kappa 1

1

0

High-throughput

0.493

High

124837

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

0

High-throughput

0.493

High

215886

ZBT14
Zinc finger and BTB domain-containing protein 14

1

0

High-throughput

0.493

High

394539

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.493

High

412134

FYN
Tyrosine-protein kinase Fyn

1

0

High-throughput

0.493

High

742217

SYUA
Alpha-synuclein

1

0

High-throughput

0.493

High

958446

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.493

High

958453

LONF2
LON peptidase N-terminal domain and RING finger protein 2

1

0

High-throughput

0.493

High

958455

FX4L6
Forkhead box protein D4-like 6

1

0

High-throughput

0.493

High

958493

SYMPK
Symplekin

1

0

High-throughput

0.493

High

958496

COA7
Cytochrome c oxidase assembly factor 7

1

0

High-throughput

0.493

High

958516

PHF23
PHD finger protein 23

1

0

High-throughput

0.493

High

958549

OCTC
Peroxisomal carnitine O-octanoyltransferase

1

0

High-throughput

0.493

High

660116

RBL1
Retinoblastoma-like protein 1

1

1

High-throughput

0.489

High

833408

RBM25
RNA-binding protein 25

1

1

High-throughput

0.489

High

958449

ELOA1
Elongin-A

1

3

High-throughput

0.489

High

958471

RSRC2
Arginine/serine-rich coiled-coil protein 2

1

1

High-throughput

0.489

High

837927

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.481

High

503897

HSP7C
Heat shock cognate 71 kDa protein

1

0

Small-scale

0.480

High

179038

TNC18
Trinucleotide repeat-containing gene 18 protein

1

1

High-throughput

0.479

High

227177

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

569593

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

779244

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

924273

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

1

Small-scale

0.479

High

958444

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.479

High

958448

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

1

High-throughput

0.479

High

958450

NONO
Non-POU domain-containing octamer-binding protein

1

2

High-throughput

0.479

High

958452

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.479

High

958518

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.479

High

958558

TRAF6
TNF receptor-associated factor 6

1

1

High-throughput

0.479

High

958459

PR38B
Pre-mRNA-splicing factor 38B

1

2

High-throughput

0.470

High

135602

NDKM
Nucleoside diphosphate kinase, mitochondrial

1

0

High-throughput

0.458

High

260021

TBCA
Tubulin-specific chaperone A

1

0

High-throughput

0.458

High

306523

NDUB8
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial

1

0

High-throughput

0.458

High

327417

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.458

High

351746

SOMA
Somatotropin

1

0

High-throughput

0.458

High

376082

CYTB
Cystatin-B

1

0

High-throughput

0.458

High

388378

HSPB1
Heat shock protein beta-1

1

0

Small-scale

0.458

High

505621

EPB41
Protein 4.1

1

0

High-throughput

0.458

High

530624

ITA4
Integrin alpha-4

1

0

High-throughput

0.458

High

552501

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

617517

CRCM
Colorectal mutant cancer protein

1

0

High-throughput

0.458

High

650966

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

771910

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.458

High

777441

MDHC
Malate dehydrogenase, cytoplasmic

1

0

High-throughput

0.458

High

821170

TCPE
T-complex protein 1 subunit epsilon

1

0

High-throughput

0.458

High

854773

GDIR1
Rho GDP-dissociation inhibitor 1

1

0

High-throughput

0.458

High

874826

TERA
Transitional endoplasmic reticulum ATPase

1

0

Small-scale

0.458

High

885776

MTPN
Myotrophin

1

0

High-throughput

0.458

High

896415

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

0

High-throughput

0.458

High

920756

RS28
Small ribosomal subunit protein eS28

1

0

High-throughput

0.458

High

940787

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

949098

LACTB
Serine beta-lactamase-like protein LACTB, mitochondrial

1

0

High-throughput

0.458

High

958439

B2CL1
Bcl-2-like protein 1

1

0

Small-scale

0.458

High

958445

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

958447

DX39B
Spliceosome RNA helicase DDX39B

1

0

High-throughput

0.458

High

958451

ELAV1
ELAV-like protein 1

1

0

Small-scale

0.458

High

958456

MIX23
Protein MIX23

1

0

High-throughput

0.458

High

958460

MIC13
MICOS complex subunit MIC13

1

0

High-throughput

0.458

High

958462

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

958465

ETFR1
Electron transfer flavoprotein regulatory factor 1

1

0

High-throughput

0.458

High

958473

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

958476

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

958487

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

1

0

High-throughput

0.458

High

958489

TITIN
Titin

1

0

High-throughput

0.458

High

958495

PINX1
PIN2/TERF1-interacting telomerase inhibitor 1

1

0

High-throughput

0.458

High

958497

OPTN
Optineurin

1

0

High-throughput

0.458

High

958499

OMA1
Metalloendopeptidase OMA1, mitochondrial

1

0

High-throughput

0.458

High

958503

FMC1
Protein FMC1 homolog

1

0

High-throughput

0.458

High

958507

IMP1L
Mitochondrial inner membrane protease subunit 1

1

0

High-throughput

0.458

High

958508

YMEL1
ATP-dependent zinc metalloprotease YME1L1

1

0

High-throughput

0.458

High

958510

COQ7
5-demethoxyubiquinone hydroxylase, mitochondrial

1

0

High-throughput

0.458

High

958511

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.458

High

958517

MIC26
MICOS complex subunit MIC26

1

0

High-throughput

0.458

High

958520

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.458

High

958522

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

958523

CQ10B
Coenzyme Q-binding protein COQ10 homolog B, mitochondrial

1

0

High-throughput

0.458

High

958525

SFXN1
Sideroflexin-1

1

0

High-throughput

0.458

High

958526

SUCHY
Succinate--hydroxymethylglutarate CoA-transferase

1

0

High-throughput

0.458

High

958527

PPA6
Lysophosphatidic acid phosphatase type 6

1

0

High-throughput

0.458

High

958529

ARHG4
Rho guanine nucleotide exchange factor 4

1

0

High-throughput

0.458

High

958536

GMIP
GEM-interacting protein

1

0

High-throughput

0.458

High

958541

HDAC6
Histone deacetylase 6

1

0

High-throughput

0.458

High

958542

DJB11
DnaJ homolog subfamily B member 11

1

0

High-throughput

0.458

High

958544

TRM7
tRNA

1

0

High-throughput

0.458

High

958545

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

958546

TES
Testin

1

0

High-throughput

0.458

High

958548

TNIK
TRAF2 and NCK-interacting protein kinase

1

0

High-throughput

0.458

High

958554

COQ6
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial

1

0

High-throughput

0.458

High

958556

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

0

High-throughput

0.458

High

958557

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.458

High

601214

VDAC1
Voltage-dependent anion-selective channel protein 1

1

2

Small-scale

0.445

High

547785

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

0

High-throughput

0.426

High

958492

ESR2
Estrogen receptor beta

1

0

High-throughput

0.426

High

581676

VCAM1
Vascular cell adhesion protein 1

1

1

High-throughput

0.407

High

362650

A2GL
Leucine-rich alpha-2-glycoprotein

2

0

High-throughput

0.328

High

958437

CAV1
Caveolin-1

2

0

High-throughput

0.298

High

958512

SH3G3
Endophilin-A3

2

0

High-throughput

0.298

High

958475

SUGP1
SURP and G-patch domain-containing protein 1

1

0

High-throughput

0.279

Low

958498

PAUF
Pancreatic adenocarcinoma up-regulated factor

1

0

High-throughput

0.279

Low

958501

RRP36
Ribosomal RNA processing protein 36 homolog

1

0

High-throughput

0.279

Low

958513

SELS
Selenoprotein S

1

0

High-throughput

0.279

Low

958521

ESF1
ESF1 homolog

1

0

High-throughput

0.279

Low

958555

UTP11
Probable U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.279

Low

958454

CC036
Uncharacterized protein C3orf36

1

0

High-throughput

0.268

Low

958461

RUAS1
Putative uncharacterized protein RUSC1-AS1

1

0

High-throughput

0.268

Low

958466

ASCL4
Achaete-scute homolog 4

1

0

High-throughput

0.268

Low

958467

PPR21
Protein phosphatase 1 regulatory subunit 21

1

0

High-throughput

0.268

Low

958477

LRC56
Leucine-rich repeat-containing protein 56

1

0

High-throughput

0.268

Low

958478

FAM9A
Protein FAM9A

1

0

High-throughput

0.268

Low

958480

KCD17
BTB/POZ domain-containing protein KCTD17

1

0

High-throughput

0.268

Low

958531

SEM4G
Semaphorin-4G

1

0

High-throughput

0.268

Low

62725

DDTL
D-dopachrome decarboxylase-like protein

1

0

High-throughput

0.249

Low

354420

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.249

Low

720236

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

958468

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

958486

SPT20
Spermatogenesis-associated protein 20

1

0

High-throughput

0.249

Low

958494

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.249

Low

958504

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

958539

HECW2
E3 ubiquitin-protein ligase HECW2

1

0

High-throughput

0.249

Low

958540

TR10D
Tumor necrosis factor receptor superfamily member 10D

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024