Interactor 1: HP1 (P05205)
Heterochromatin protein 1 (HP1) (Non-histone chromosomal protein C1A9 antigen)
Gene: Su(var)205

Interactor 2: SUV39 (P45975)
Histone-lysine N-methyltransferase Su(var)3-9 (EC 2.1.1.355) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (Lysine N-methyltransferase 1) (Protein suppressor of variegation 3-9)
Gene: Su(var)3-9

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.969

The method score is based on:

Property Details
Experiments 24990964, 11867540, 23559249, 19352434, 30659116, 22365829, 20386606, 14605208
Identification Methods affinity chromatography technology, two hybrid, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Chromo~Chromo
Common GO terms GO:0000775 - chromosome, centromeric region
GO:0000781 - chromosome, telomeric region
GO:0000792 - heterochromatin
GO:0003682 - chromatin binding
GO:0005634 - nucleus
and 6 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 206
Dm

1 635
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+ Dm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024