HitPredict

Interactor 1: FGF1 (P05230)
Fibroblast growth factor 1 (FGF-1) (Acidic fibroblast growth factor) (aFGF) (Endothelial cell growth factor) (ECGF) (Heparin-binding growth factor 1) (HBGF-1)
Gene: FGF1

Interactor 2: Q8NI16 (Q8NI16)
Fibroblast growth factor receptor 3 (EC 2.7.10.1)
Gene: FGFR3

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	9045692
Identification Methods	coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FGF~I-set
Common GO terms	GO:0008284 - positive regulation of cell population proliferation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 155 Hs			1 771
+	Hs
		399134 FGF1_HUMAN (1-155): 2.95e-74: 220: 100.00		FGFR3_HUMAN (1-771): 0: 775: 95.47
+	Hs
		609185 FGF9_HUMAN (11-155): 6.58e-67: 203: 35.85		FGFR3_HUMAN (1-771): 0: 775: 95.47
+	Hs
		601113 FGF7_HUMAN (13-153): 1.87e-65: 199: 35.66		FGFR3_HUMAN (1-771): 0: 775: 95.47
+	Hs
		447022 FGF2_HUMAN (1-154): 7.49e-63: 196: 54.14		FGFR3_HUMAN (1-771): 0: 775: 95.47
+	Mm
		867550 FGF9_MOUSE (11-155): 7.67e-67: 203: 35.85		FGFR3_MOUSE (1-771): 0: 755: 89.00
+	Hs
		399132 FGF1_HUMAN (1-155): 2.95e-74: 220: 100.00		FGFR2_HUMAN (2-763): 0: 727: 64.48
+	Hs
		601468 FGF9_HUMAN (11-155): 6.58e-67: 203: 35.85		FGFR2_HUMAN (2-763): 0: 727: 64.48
+	Hs
		181659 FGF10_HUMAN (14-154): 5.14e-66: 201: 32.87		FGFR2_HUMAN (2-763): 0: 727: 64.48
+	Hs
		601112 FGF7_HUMAN (13-153): 1.87e-65: 199: 35.66		FGFR2_HUMAN (2-763): 0: 727: 64.48
+	Hs
		447019 FGF2_HUMAN (1-154): 7.49e-63: 196: 54.14		FGFR2_HUMAN (2-763): 0: 727: 64.48
+	Hs
		399128 FGF1_HUMAN (1-155): 2.95e-74: 220: 100.00		FGFR1_HUMAN (2-763): 0: 694: 60.46
+	Mm
		555263 FGF9_MOUSE (11-155): 7.67e-67: 203: 35.85		FGFR1_MOUSE (2-763): 0: 696: 60.59
+	Hs
		507874 FGF9_HUMAN (11-155): 6.58e-67: 203: 35.85		FGFR1_HUMAN (2-763): 0: 694: 60.46
+	Hs
		181657 FGF10_HUMAN (14-154): 5.14e-66: 201: 32.87		FGFR1_HUMAN (2-763): 0: 694: 60.46
+	Mm
		549546 FGF2_MOUSE (1-154): 9.1e-64: 194: 53.21		FGFR2_MOUSE (2-763): 0: 701: 63.45
+	Hs
		447013 FGF2_HUMAN (1-154): 7.49e-63: 196: 54.14		FGFR1_HUMAN (2-763): 0: 694: 60.46
+	Mm
		549545 FGF2_MOUSE (1-154): 9.1e-64: 194: 53.21		FGFR1_MOUSE (2-763): 0: 696: 60.59
+	Hs
		399133 FGF1_HUMAN (1-155): 2.95e-74: 220: 100.00		FGFR4_HUMAN (1-767): 0: 663: 60.49
+	Hs
		447021 FGF2_HUMAN (1-154): 7.49e-63: 196: 54.14		FGFR4_HUMAN (1-767): 0: 663: 60.49
+	Rn
		896711 FGF1_RAT (1-155): 1.38e-73: 218: 95.48		Q63237_RAT (7-378): 1.46e-141: 425: 50.79