HitPredict

Interactor 1: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Interactor 2: TCAB1 (Q9BUR4)
Telomerase Cajal body protein 1 (WD repeat-containing protein 79) (WD40 repeat-containing protein antisense to TP53 gene) (WRAP53beta)
Gene: WRAP53

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36244648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 648 Hs			1 548
+	Hs
		400614 RAF1_HUMAN (1-648): 0: 637: 100.00		GBB2_HUMAN (341-546): 1.75e-33: 132: 12.62
+	Hs
		400994 RAF1_HUMAN (1-648): 0: 637: 100.00		Q6FHM2_HUMAN (341-546): 1.75e-33: 132: 12.62
+	Hs
		400613 RAF1_HUMAN (1-648): 0: 637: 100.00		GBB1_HUMAN (294-526): 1.32e-32: 129: 10.68
+	Hs
		400627 RAF1_HUMAN (1-648): 0: 637: 100.00		RACK1_HUMAN (259-482): 1.47e-23: 103: 16.52
+	Hs
		400592 RAF1_HUMAN (1-648): 0: 637: 100.00		WDR5_HUMAN (455-548): 1.2e-18: 89.3: 9.57
+	Hs
		401279 RAF1_HUMAN (1-648): 0: 637: 100.00		SNR40_HUMAN (445-548): 3.26e-18: 88.1: 11.43
+	Hs
		578540 BRAF_HUMAN (39-647): 9.6e-166: 494: 56.02		TBL1R_HUMAN (320-548): 5.71e-38: 148: 10.70
+	Dm
		198131 KRAF1_DROME (45-647): 8.65e-166: 494: 44.98		GBLP_DROME (259-482): 1.75e-23: 103: 16.96
+	Hs
		521298 ARAF_HUMAN (44-646): 8.15e-165: 486: 59.18		RACK1_HUMAN (259-482): 1.47e-23: 103: 16.52
+	Hs
		440480 FYN_HUMAN (337-607): 1.87e-103: 326: 34.55		GBB1_HUMAN (294-526): 1.32e-32: 129: 10.68
+	Hs
		557207 SRC_HUMAN (331-607): 2.21e-106: 334: 33.45		RACK1_HUMAN (259-482): 1.47e-23: 103: 16.52
+	Hs
		440482 FYN_HUMAN (337-607): 1.87e-103: 326: 34.55		RACK1_HUMAN (259-482): 1.47e-23: 103: 16.52
+	Hs
		440671 FYN_HUMAN (337-607): 1.87e-103: 326: 34.55		SNR40_HUMAN (445-548): 3.26e-18: 88.1: 11.43
+	Hs
		1250423 KSR2_HUMAN (332-623): 6.75e-43: 168: 34.43		TBL1R_HUMAN (320-548): 5.71e-38: 148: 10.70
+	Zm
		38108 A0A1D6NRI5_MAIZE (315-633): 4.59e-40: 159: 30.81		A0A1D6MEH7_MAIZE (6-196): 1.49e-14: 78.1: 8.90