Protein: KSR2
Kinase suppressor of Ras 2 (hKSR2) (EC 2.7.11.1)

Gene: KSR2
Organism: Homo sapiens
Interactions: 51
UniProt ID: Q6VAB6

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005078 - MAP-kinase scaffold activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1038311

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

3

20

Small-scale

0.867

High

461612

HS90A
Heat shock protein HSP 90-alpha

3

20

High-throughput

0.847

High

783606

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

2

20

High-throughput

0.811

High

966493

1433G
14-3-3 protein gamma

2

20

High-throughput

0.811

High

971668

1433E
14-3-3 protein epsilon

2

10

High-throughput

0.811

High

1105976

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

2

17

High-throughput

0.789

High

1158390

CDC37
Hsp90 co-chaperone Cdc37

2

20

High-throughput

0.789

High

691148

1433T
14-3-3 protein theta

1

20

High-throughput

0.691

High

729970

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.691

High

955308

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.691

High

990376

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.691

High

1049448

1433F
14-3-3 protein eta

1

20

High-throughput

0.691

High

834750

M3K8
Mitogen-activated protein kinase kinase kinase 8

1

20

Small-scale

0.665

High

276696

FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6

1

15

High-throughput

0.618

High

401022

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

19

Small-scale

0.618

High

468515

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.618

High

578503

BRAF
Serine/threonine-protein kinase B-raf

1

18

Small-scale

0.618

High

703626

MK01
Mitogen-activated protein kinase 1

1

15

Small-scale

0.618

High

1095394

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

9

Small-scale

0.618

High

1245550

Q6PK50
HSP90AB1 protein

1

20

High-throughput

0.618

High

1202053

HS905
Putative heat shock protein HSP 90-alpha A5

1

20

High-throughput

0.575

High

208522

PJA2
E3 ubiquitin-protein ligase Praja-2

1

5

Small-scale

0.561

High

182147

PFD6
Prefoldin subunit 6

1

2

High-throughput

0.536

High

185792

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

4

High-throughput

0.536

High

316403

RMP
Unconventional prefoldin RPB5 interactor 1

1

1

High-throughput

0.536

High

621900

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

1

High-throughput

0.536

High

854125

KI67
Proliferation marker protein Ki-67

1

11

High-throughput

0.536

High

873470

PP2BC
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform

1

16

High-throughput

0.536

High

888138

MCM2
DNA replication licensing factor MCM2

1

5

High-throughput

0.536

High

916672

PPP5
Serine/threonine-protein phosphatase 5

1

20

High-throughput

0.536

High

1250416

WAPL
Wings apart-like protein homolog

1

1

High-throughput

0.536

High

1250417

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

8

High-throughput

0.536

High

1250419

GASP2
G-protein coupled receptor-associated sorting protein 2

1

3

High-throughput

0.536

High

1250420

DC2I2
Cytoplasmic dynein 2 intermediate chain 2

1

9

High-throughput

0.536

High

1250425

RPAP3
RNA polymerase II-associated protein 3

1

9

High-throughput

0.536

High

165051

RPC1
DNA-directed RNA polymerase III subunit RPC1

1

0

High-throughput

0.513

High

192017

GLYG2
Glycogenin-2

1

0

High-throughput

0.513

High

1250427

PDRG1
p53 and DNA damage-regulated protein 1

1

0

High-throughput

0.513

High

1250428

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.513

High

1250421

DAA10
Dynein axonemal assembly factor 10

1

1

High-throughput

0.489

High

1250423

TBL1R
F-box-like/WD repeat-containing protein TBL1XR1

1

7

High-throughput

0.489

High

1250424

CPVL
Probable serine carboxypeptidase CPVL

1

2

High-throughput

0.489

High

950546

KR108
Keratin-associated protein 10-8

1

7

High-throughput

0.481

High

872453

SOX2
Transcription factor SOX-2

1

2

High-throughput

0.479

High

1250415

CSN6
COP9 signalosome complex subunit 6

1

2

High-throughput

0.479

High

1250418

Q96BE0
Heat shock cognate 71 kDa protein

1

12

High-throughput

0.479

High

1250426

NGB
Neuroglobin

1

0

High-throughput

0.458

High

76548

B4DYC6
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1

1

1

High-throughput

0.437

High

1250422

Q9BPW0
Serine/threonine-protein phosphatase

1

19

High-throughput

0.437

High

70297

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

1250429

NDUBB
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025