HitPredict

Interactor 1: LA (P05455)
Lupus La protein (La autoantigen) (La ribonucleoprotein) (Sjoegren syndrome type B antigen) (SS-B)
Gene: SSB

Interactor 2: SERB1 (Q8NC51)
SERPINE1 mRNA-binding protein 1 (PAI1 RNA-binding protein 1) (PAI-RBP1) (Plasminogen activator inhibitor 1 RNA-binding protein)
Gene: SERBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 34349018
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 408 Hs			1 408
+	Hs
		1116396 LARP7_HUMAN (7-177): 1.36e-38: 148: 29.48		SERB1_HUMAN (1-408): 2.24e-144: 418: 100.00
+	Mm
		857377 TIA1_MOUSE (106-327): 7.74e-43: 156: 14.16		SERB1_MOUSE (1-408): 5.15e-141: 409: 98.28
+	Hs
		1162610 LARP1_HUMAN (13-110): 5.89e-22: 100: 39.39		SERB1_HUMAN (1-408): 2.24e-144: 418: 100.00
+	Hs
		1145687 LAR1B_HUMAN (11-95): 1.3e-15: 81: 38.82		SERB1_HUMAN (1-408): 2.24e-144: 418: 100.00
+	Hs
		1174821 LARP4_HUMAN (13-169): 2.91e-12: 70.2: 19.50		SERB1_HUMAN (1-408): 2.24e-144: 418: 100.00
+	Hs
		1031392 PABP4_HUMAN (236-313): 1.06e-10: 65.3: 17.07		SERB1_HUMAN (1-408): 2.24e-144: 418: 100.00
+	Hs
		516591 PABP1_HUMAN (223-313): 1.11e-10: 65.3: 17.90		SERB1_HUMAN (1-408): 2.24e-144: 418: 100.00
+	Hs
		1116307 LARP7_HUMAN (7-177): 1.36e-38: 148: 29.48		HABP4_HUMAN (5-408): 8.65e-102: 309: 35.68