HitPredict

Interactor 1: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Interactor 2: CCDC6 (Q16204)
Coiled-coil domain-containing protein 6 (Papillary thyroid carcinoma-encoded protein) (Protein H4)
Gene: CCDC6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 285 Hs			1 474
+	Hs
		451290 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		RUFY2_HUMAN (59-346): 8.08e-24: 106: 19.87
+	Dm
		419108 TPM1_DROME (2-282): 8.67e-51: 171: 45.97		MYSN_DROME (33-428): 2.04e-10: 65.4: 9.85
+	Hs
		418895 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78
+	Hs
		451201 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78
+	Hs
		419011 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		MY18A_HUMAN (62-328): 1.49e-10: 65.8: 15.87
+	Hs
		451293 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		MY18A_HUMAN (62-328): 1.49e-10: 65.8: 15.87
+	Hs
		148289 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		CTRO_HUMAN (50-352): 1.81e-09: 62.3: 11.78
+	Hs
		434354 TPM2_HUMAN (2-285): 1.42e-39: 141: 86.27		MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78
+	Hs
		434415 TPM2_HUMAN (2-285): 1.42e-39: 141: 86.27		MY18A_HUMAN (62-328): 1.49e-10: 65.8: 15.87
+	Hs
		724765 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78
+	Hs
		932031 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		MY18A_HUMAN (62-328): 1.49e-10: 65.8: 15.87
+	Hs
		148661 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		CTRO_HUMAN (50-352): 1.81e-09: 62.3: 11.78
+	Hs
		1201957 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		TAXB1_HUMAN (59-365): 6.01e-28: 119: 20.46
+	Rn
		1186812 MRCKB_RAT (3-285): 1.56e-12: 69.5: 14.09		MRCKB_RAT (23-351): 1.72e-21: 100: 15.25
+	Hs
		1268126 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		MY18A_HUMAN (62-328): 1.49e-10: 65.8: 15.87
+	Hs
		110796 H7BYY1_HUMAN (2-228): 1.39e-10: 62.2: 21.37		MYH9_HUMAN (4-401): 5.49e-12: 70.4: 11.78
+	Hs
		110802 H7BYY1_HUMAN (2-228): 1.39e-10: 62.2: 21.37		MY18A_HUMAN (62-328): 1.49e-10: 65.8: 15.87