Interactor 1: ITB1 (P05556)
Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)
Gene: ITGB1

Interactor 2: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 0.60 0.633

The method score is based on:

Property Details
Experiments 34079125, 20159608, 14593208
Identification Methods proximity labelling technology, anti bait coimmunoprecipitation, enzyme linked immunosorbent assay
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005178 - integrin binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0009986 - cell surface
GO:0030335 - positive regulation of cell migration
and 4 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 798
Hs

1 512
+ Mm
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+ Rn
+ Hs
+ Hs
+ Mm
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+ Mm
+ Hs
+ Hs
+ Dm
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+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024