Protein: ERR2
Steroid hormone receptor ERR2 (ERR beta-2) (Estrogen receptor-like 2) (Estrogen-related receptor beta) (ERR-beta) (Nuclear receptor subfamily 3 group B member 2)

Gene: ERR2, ESRRB
Organism: Homo sapiens
Interactions: 99
UniProt ID: O95718

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000793 - condensed chromosome
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 - cis-regulatory region sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

343246

ERR3
Estrogen-related receptor gamma

3

20

High-throughput

0.858

High

343207

HS90A
Heat shock protein HSP 90-alpha

2

19

Small-scale

0.800

High

343210

HS90B
Heat shock protein HSP 90-beta

2

19

Small-scale

0.800

High

343215

ERR1
Steroid hormone receptor ERR1

1

19

High-throughput

0.691

High

343259

NCOA2
Nuclear receptor coactivator 2

1

20

Small-scale

0.647

High

343289

NCOA3
Nuclear receptor coactivator 3

1

20

Small-scale

0.647

High

343271

ESR2
Estrogen receptor beta

1

19

High-throughput

0.618

High

343275

PKP2
Plakophilin-2

1

20

High-throughput

0.618

High

343262

HIF1A
Hypoxia-inducible factor 1-alpha

1

20

Small-scale

0.561

High

343237

SPB4
Serpin B4

1

8

High-throughput

0.536

High

343288

ARIP4
Helicase ARIP4

1

20

High-throughput

0.536

High

343208

SP1
Transcription factor Sp1

1

20

Small-scale

0.501

High

343236

NRIP1
Nuclear receptor-interacting protein 1

1

15

Small-scale

0.501

High

343266

O11G2
Olfactory receptor 11G2

1

1

High-throughput

0.489

High

240390

PRKN
E3 ubiquitin-protein ligase parkin

1

7

Small-scale

0.479

High

258697

DNJA2
DnaJ homolog subfamily A member 2

1

13

High-throughput

0.479

High

274423

DNJB6
DnaJ homolog subfamily B member 6

1

17

High-throughput

0.479

High

332809

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

4

High-throughput

0.479

High

343198

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

20

High-throughput

0.479

High

343199

EGFR
Epidermal growth factor receptor

1

10

High-throughput

0.479

High

343201

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

4

High-throughput

0.479

High

343202

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

11

High-throughput

0.479

High

343204

ADT2
ADP/ATP translocase 2

1

11

High-throughput

0.479

High

343205

ANXA2
Annexin A2

1

7

High-throughput

0.479

High

343206

TBB5
Tubulin beta chain

1

12

High-throughput

0.479

High

343209

4F2
Amino acid transporter heavy chain SLC3A2

1

2

High-throughput

0.479

High

343212

CH60
60 kDa heat shock protein, mitochondrial

1

7

High-throughput

0.479

High

343213

BIP
Endoplasmic reticulum chaperone BiP

1

18

High-throughput

0.479

High

343214

HSP7C
Heat shock cognate 71 kDa protein

1

14

High-throughput

0.479

High

343216

ADT3
ADP/ATP translocase 3

1

11

High-throughput

0.479

High

343217

GFAP
Glial fibrillary acidic protein

1

18

High-throughput

0.479

High

343218

RS2
Small ribosomal subunit protein uS5

1

3

High-throughput

0.479

High

343219

GBB3
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3

1

20

High-throughput

0.479

High

343221

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.479

High

343222

DNJB2
DnaJ homolog subfamily B member 2

1

13

High-throughput

0.479

High

343224

1433T
14-3-3 protein theta

1

17

High-throughput

0.479

High

343226

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

5

High-throughput

0.479

High

343227

DNJA1
DnaJ homolog subfamily A member 1

1

13

High-throughput

0.479

High

343228

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

20

High-throughput

0.479

High

343230

PHB1
Prohibitin 1

1

9

High-throughput

0.479

High

343232

HSPA9
Stress-70 protein, mitochondrial

1

20

High-throughput

0.479

High

343233

RS27
Small ribosomal subunit protein eS27

1

4

High-throughput

0.479

High

343234

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

3

High-throughput

0.479

High

343239

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

20

High-throughput

0.479

High

343240

TXTP
Tricarboxylate transport protein, mitochondrial

1

16

High-throughput

0.479

High

343241

HNRH2
Heterogeneous nuclear ribonucleoprotein H2

1

20

High-throughput

0.479

High

343244

RS16
Small ribosomal subunit protein uS9

1

6

High-throughput

0.479

High

343245

RS14
Small ribosomal subunit protein uS11

1

2

High-throughput

0.479

High

343247

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

9

High-throughput

0.479

High

343248

RL23
Large ribosomal subunit protein uL14

1

3

High-throughput

0.479

High

343249

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

20

High-throughput

0.479

High

343250

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

20

High-throughput

0.479

High

343251

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

10

High-throughput

0.479

High

343252

GRB2
Growth factor receptor-bound protein 2

1

17

High-throughput

0.479

High

343253

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

9

High-throughput

0.479

High

343254

EF1A1
Elongation factor 1-alpha 1

1

9

High-throughput

0.479

High

343255

TBA1B
Tubulin alpha-1B chain

1

15

High-throughput

0.479

High

343258

EF1A2
Elongation factor 1-alpha 2

1

9

High-throughput

0.479

High

343260

NF2L2
Nuclear factor erythroid 2-related factor 2

1

9

Small-scale

0.479

High

343261

CDC37
Hsp90 co-chaperone Cdc37

1

1

High-throughput

0.479

High

343264

RS27L
Ribosomal protein eS27-like

1

4

High-throughput

0.479

High

343267

DNJB8
DnaJ homolog subfamily B member 8

1

17

High-throughput

0.479

High

343268

UBS3B
Ubiquitin-associated and SH3 domain-containing protein B

1

8

High-throughput

0.479

High

343270

S39A7
Zinc transporter SLC39A7

1

5

High-throughput

0.479

High

343273

S10AG
Protein S100-A16

1

16

High-throughput

0.479

High

343274

PHB2
Prohibitin-2

1

9

High-throughput

0.479

High

343276

TBA1C
Tubulin alpha-1C chain

1

15

High-throughput

0.479

High

343278

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

20

High-throughput

0.479

High

343279

SPTN4
Spectrin beta chain, non-erythrocytic 4

1

20

High-throughput

0.479

High

343280

GBB4
Guanine nucleotide-binding protein subunit beta-4

1

20

High-throughput

0.479

High

343282

PKDRE
Polycystin family receptor for egg jelly

1

7

High-throughput

0.479

High

343285

VAPA
Vesicle-associated membrane protein-associated protein A

1

4

High-throughput

0.479

High

343287

ERRFI
ERBB receptor feedback inhibitor 1

1

14

High-throughput

0.479

High

343263

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

0

High-throughput

0.458

High

337656

SGPL1
Sphingosine-1-phosphate lyase 1

1

4

High-throughput

0.437

High

339383

ACSL3
Fatty acid CoA ligase Acsl3

1

4

High-throughput

0.437

High

343200

TFR1
Transferrin receptor protein 1

1

5

High-throughput

0.437

High

343203

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

6

High-throughput

0.437

High

343211

MGST1
Microsomal glutathione S-transferase 1

1

1

High-throughput

0.437

High

343220

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

7

High-throughput

0.437

High

343223

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

1

6

High-throughput

0.437

High

343225

CALX
Calnexin

1

3

High-throughput

0.437

High

343229

ERD22
ER lumen protein-retaining receptor 2

1

3

High-throughput

0.437

High

343231

ATPG
ATP synthase F(1) complex subunit gamma, mitochondrial

1

2

High-throughput

0.437

High

343235

SSRA
Translocon-associated protein subunit alpha

1

3

High-throughput

0.437

High

343238

EFTU
Elongation factor Tu, mitochondrial

1

10

High-throughput

0.437

High

343242

TMM33
Transmembrane protein 33

1

1

High-throughput

0.437

High

343256

S25A3
Solute carrier family 25 member 3

1

18

High-throughput

0.437

High

343257

TNAP2
Tumor necrosis factor alpha-induced protein 2

1

1

High-throughput

0.437

High

343265

DJC10
DnaJ homolog subfamily C member 10

1

13

High-throughput

0.437

High

343269

THEM6
Protein THEM6

1

2

High-throughput

0.437

High

343272

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

7

High-throughput

0.437

High

343281

S10AE
Protein S100-A14

1

16

High-throughput

0.437

High

343283

ATD3A
ATPase family AAA domain-containing protein 3A

1

18

High-throughput

0.437

High

343284

HACD3
Very-long-chain

1

7

High-throughput

0.437

High

343286

DHCR7
7-dehydrocholesterol reductase

1

3

High-throughput

0.437

High

137601

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.249

Low

343243

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

0

High-throughput

0.249

Low

343277

TIM21
Mitochondrial import inner membrane translocase subunit Tim21

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025