HitPredict

Interactor 1: JUN (P05627)
Transcription factor Jun (AH119) (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (Jun A)
Gene: JUN

Interactor 2: CCL7 (Q03366)
C-C motif chemokine 7 (Intercrine/chemokine MARC) (Monocyte chemoattractant protein 3) (Monocyte chemotactic protein 3) (MCP-3) (Protein FIC) (Small-inducible cytokine A7)
Gene: CCL7

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19299558
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070374 - positive regulation of ERK1 and ERK2 cascade
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 334 Mm			1 97
+	Mm
		404109 JUN_MOUSE (1-334): 1.42e-101: 303: 100.00		CCL2_MOUSE (1-97): 5.79e-33: 113: 45.46
+	Mm
		404144 JUN_MOUSE (1-334): 1.42e-101: 303: 100.00		CCL12_MOUSE (1-94): 3.02e-32: 110: 54.17
+	Mm
		404114 JUN_MOUSE (1-334): 1.42e-101: 303: 100.00		CCL4_MOUSE (1-91): 5.64e-27: 96.2: 32.61
+	Hs
		402085 JUN_HUMAN (1-334): 5.59e-99: 296: 94.61		CCL14_HUMAN (1-91): 1.26e-29: 103: 28.72
+	Mm
		500592 ATF7_MOUSE (49-332): 1.7e-48: 169: 19.80		CCL3_MOUSE (1-92): 3.11e-34: 114: 35.48
+	Hs
		486222 CREB1_HUMAN (36-310): 2.27e-35: 132: 16.56		CCL3_HUMAN (1-92): 6.62e-33: 111: 28.26
+	Hs
		526555 CREB1_HUMAN (36-310): 2.27e-35: 132: 16.56		CCL4_HUMAN (1-91): 1.18e-31: 108: 33.70
+	Hs
		528231 ATF2_HUMAN (44-334): 1.1e-40: 150: 19.02		CCL5_HUMAN (1-91): 3.23e-24: 89.2: 35.87
+	Hs
		528232 CREB1_HUMAN (36-310): 2.27e-35: 132: 16.56		CCL5_HUMAN (1-91): 3.23e-24: 89.2: 35.87
+	Hs
		1246073 CR3L1_HUMAN (88-308): 5.13e-31: 124: 16.74		CC4L_HUMAN (1-91): 4.63e-27: 96.6: 34.78