Protein: S27A3
Long-chain fatty acid transport protein 3 (FATP-3) (Fatty acid transport protein 3) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Solute carrier family 27 member 3) (Very long-chain acyl-CoA synthetase homolog 3) (VLCS-3) (EC 6.2.1.-)

Gene: S27A3, SLC27A3
Organism: Homo sapiens
Interactions: 105
UniProt ID: Q5K4L6

Gene Ontology (top 5):
GO:0001676 - long-chain fatty acid metabolic process
GO:0004467 - long-chain fatty acid-CoA ligase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1207884

ZNRF4
E3 ubiquitin-protein ligase ZNRF4

3

6

High-throughput

0.667

High

212418

SPIT2
Kunitz-type protease inhibitor 2

3

0

High-throughput

0.638

High

1207907

LIMD1
LIM domain-containing protein 1

3

0

High-throughput

0.634

High

443819

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

2

1

High-throughput

0.628

High

850876

KI3L2
Killer cell immunoglobulin-like receptor 3DL2

2

6

High-throughput

0.628

High

1057545

ACHD
Acetylcholine receptor subunit delta

2

3

High-throughput

0.628

High

1207896

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

2

1

High-throughput

0.628

High

1006013

ASIC1
Acid-sensing ion channel 1

2

0

High-throughput

0.602

High

1207870

SYVN1
E3 ubiquitin-protein ligase synoviolin

2

8

High-throughput

0.571

High

1207887

ERLEC
Endoplasmic reticulum lectin 1

2

1

High-throughput

0.549

High

64875

RCCD1
RCC1 domain-containing protein 1

1

7

High-throughput

0.536

High

182566

GP182
G-protein coupled receptor 182

1

9

High-throughput

0.536

High

347747

BAG3
BAG family molecular chaperone regulator 3

1

4

High-throughput

0.536

High

537295

HSP7C
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.536

High

595054

KCNA2
Potassium voltage-gated channel subfamily A member 2

1

3

High-throughput

0.536

High

640518

TA2R
Thromboxane A2 receptor

1

2

High-throughput

0.536

High

722853

SSR1
Somatostatin receptor type 1

1

2

High-throughput

0.536

High

761703

HSP74
Heat shock 70 kDa protein 4

1

9

High-throughput

0.536

High

946556

EVA1C
Protein eva-1 homolog C

1

3

High-throughput

0.536

High

1010477

EREP3
Protein ENTREP3

1

2

High-throughput

0.536

High

1085323

SCAP
Sterol regulatory element-binding protein cleavage-activating protein

1

4

High-throughput

0.536

High

1126298

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

5

High-throughput

0.536

High

1195432

NKAI1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

1

2

High-throughput

0.536

High

1203674

TTMP
TPA-induced transmembrane protein

1

4

High-throughput

0.536

High

1207865

LRFN4
Leucine-rich repeat and fibronectin type-III domain-containing protein 4

1

7

High-throughput

0.536

High

1207869

T150A
Transmembrane protein 150A

1

1

High-throughput

0.536

High

1207874

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

1

High-throughput

0.536

High

1207875

LRTM2
Leucine-rich repeat and transmembrane domain-containing protein 2

1

6

High-throughput

0.536

High

1207885

AQP3
Aquaporin-3

1

3

High-throughput

0.536

High

1207888

TSN17
Tetraspanin-17

1

6

High-throughput

0.536

High

1207890

ZDH12
Palmitoyltransferase ZDHHC12

1

3

High-throughput

0.536

High

1207897

TTYH1
Protein tweety homolog 1

1

2

High-throughput

0.536

High

1207899

KCMB3
Calcium-activated potassium channel subunit beta-3

1

1

High-throughput

0.536

High

1207900

CP26B
Cytochrome P450 26B1

1

1

High-throughput

0.536

High

1207901

EVA1B
Protein eva-1 homolog B

1

3

High-throughput

0.536

High

1207903

PCD10
Protocadherin-10

1

8

High-throughput

0.536

High

1207909

CHIP
E3 ubiquitin-protein ligase CHIP

1

8

High-throughput

0.536

High

1207911

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

2

High-throughput

0.536

High

1207913

PCDB3
Protocadherin beta-3

1

8

High-throughput

0.536

High

1207914

PCDGH
Protocadherin gamma-B5

1

8

High-throughput

0.536

High

1207915

GPR45
Probable G-protein coupled receptor 45

1

5

High-throughput

0.536

High

47910

S12A8
Solute carrier family 12 member 8

1

5

High-throughput

0.515

High

376611

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

0

High-throughput

0.513

High

397801

ATP8
ATP synthase F(0) complex subunit 8

1

0

High-throughput

0.513

High

665609

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

1

0

High-throughput

0.513

High

716688

ATPD
ATP synthase F(1) complex subunit delta, mitochondrial

1

0

High-throughput

0.513

High

944915

TMPS3
Transmembrane protease serine 3

1

0

High-throughput

0.513

High

1088773

NMDE1
Glutamate receptor ionotropic, NMDA 2A

1

0

High-throughput

0.513

High

1204513

XKR6
XK-related protein 6

1

0

High-throughput

0.513

High

1207864

TM268
Transmembrane protein 268

1

0

High-throughput

0.513

High

1207871

LHPL1
LHFPL tetraspan subfamily member 1 protein

1

0

High-throughput

0.513

High

1207876

SIDT2
SID1 transmembrane family member 2

1

0

High-throughput

0.513

High

1207880

TLC3A
TLC domain-containing protein 3A

1

0

High-throughput

0.513

High

1207883

CC107
Coiled-coil domain-containing protein 107

1

0

High-throughput

0.513

High

1207891

KCNKG
Potassium channel subfamily K member 16

1

0

High-throughput

0.513

High

410889

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

6

High-throughput

0.500

High

777704

VGFR3
Vascular endothelial growth factor receptor 3

1

1

High-throughput

0.500

High

66440

ASB14
Ankyrin repeat and SOCS box protein 14

1

3

High-throughput

0.489

High

295590

CIB2
Calcium and integrin-binding family member 2

1

3

High-throughput

0.489

High

700787

DMB
HLA class II histocompatibility antigen, DM beta chain

1

5

High-throughput

0.489

High

850896

KI2S2
Killer cell immunoglobulin-like receptor 2DS2

1

2

High-throughput

0.479

High

869604

SC6A8
Sodium- and chloride-dependent creatine transporter 1

1

2

Small-scale

0.479

High

1042749

PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor

1

4

High-throughput

0.479

High

1113303

CUL3
Cullin-3

1

4

High-throughput

0.479

High

1155149

EREP1
Endosomal transmembrane epsin interactor 1

1

2

High-throughput

0.479

High

1207866

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

1207877

RN149
E3 ubiquitin-protein ligase RNF149

1

6

High-throughput

0.479

High

1207886

ESR2
Estrogen receptor beta

1

6

High-throughput

0.479

High

1207889

RN185
E3 ubiquitin-protein ligase RNF185

1

3

High-throughput

0.479

High

1207894

DERL1
Derlin-1

1

1

High-throughput

0.479

High

1207898

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.479

High

1207908

S12A6
Solute carrier family 12 member 6

1

6

Small-scale

0.479

High

218277

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

582577

PPAP
Prostatic acid phosphatase

1

0

High-throughput

0.458

High

1207873

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.458

High

1207881

MCLN3
Mucolipin-3

1

0

High-throughput

0.458

High

291368

NU155
Nuclear pore complex protein Nup155

1

3

High-throughput

0.445

High

563874

CFTR
Cystic fibrosis transmembrane conductance regulator

1

6

High-throughput

0.445

High

575141

IDE
Insulin-degrading enzyme

1

2

High-throughput

0.445

High

856726

BAG6
Large proline-rich protein BAG6

1

1

High-throughput

0.445

High

1103542

PDE3B
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B

1

3

High-throughput

0.445

High

1105470

OS9
Protein OS-9

1

1

High-throughput

0.445

High

1158221

RM23
Large ribosomal subunit protein uL23m

1

1

High-throughput

0.445

High

1207862

PR15B
Protein phosphatase 1 regulatory subunit 15B

1

4

High-throughput

0.445

High

1207872

CTL2
Choline transporter-like protein 2

1

1

High-throughput

0.445

High

1207878

CTL5
Choline transporter-like protein 5

1

1

High-throughput

0.445

High

1207893

COR1B
Coronin-1B

1

2

High-throughput

0.445

High

1207895

S12A9
Solute carrier family 12 member 9

1

6

High-throughput

0.445

High

1207906

SE1L1
Protein sel-1 homolog 1

1

2

High-throughput

0.445

High

1207910

S12A4
Solute carrier family 12 member 4

1

6

High-throughput

0.445

High

1207912

UB2J1
Ubiquitin-conjugating enzyme E2 J1

1

1

High-throughput

0.445

High

1207916

S12A7
Solute carrier family 12 member 7

1

6

High-throughput

0.445

High

830872

CCNF
Cyclin-F

1

4

High-throughput

0.437

High

1207867

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.437

High

1207892

RING2
E3 ubiquitin-protein ligase RING2

1

3

High-throughput

0.437

High

1207904

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

1

High-throughput

0.437

High

117222

SIM22
Small integral membrane protein 22

1

0

Small-scale

0.426

High

868056

OR1D4
Olfactory receptor 1D4

1

0

High-throughput

0.426

High

1207879

CNNM3
Metal transporter CNNM3

1

0

High-throughput

0.426

High

1207863

HECD3
E3 ubiquitin-protein ligase HECTD3

1

9

High-throughput

0.407

High

1207882

THEM6
Protein THEM6

1

1

High-throughput

0.407

High

49784

CLRN2
Clarin-2

1

0

High-throughput

0.279

Low

1207902

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

0

High-throughput

0.279

Low

1207868

GET4
Golgi to ER traffic protein 4 homolog

1

0

High-throughput

0.232

Low

1207905

FA8A1
Protein FAM8A1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025