Interactor 1: ERBB2 (P04626)
Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Metastatic lymph node gene 19 protein) (MLN 19) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (Tyrosine kinase-type cell surface receptor HER2) (p185erbB2) (CD antigen CD340)
Gene: ERBB2
Interactor 2: RTN4R (Q9BZR6)
Reticulon-4 receptor (Nogo receptor) (NgR) (Nogo-66 receptor)
Gene: RTN4R
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 39499777 |
| Identification Methods | proximity labelling technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | GF_recep_IV~LRR_8, LRR_8~PK_Tyr_Ser-Thr |
| Common GO terms | GO:0005886 - plasma membrane GO:0007166 - cell surface receptor signaling pathway GO:0035025 - positive regulation of Rho protein signal transduction |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
