Protein: EGFR
Epidermal growth factor receptor (EC 2.7.10.1)

Gene: EGFR
Organism: Mus musculus
Interactions: 39
UniProt ID: Q01279

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0000902 - cell morphogenesis
GO:0001892 - embryonic placenta development
GO:0001934 - positive regulation of protein phosphorylation
GO:0001942 - hair follicle development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1030069

GRB2
Growth factor receptor-bound protein 2

9

20

Small-scale

0.970

High

1022210

SHC1
SHC-transforming protein 1

4

20

Small-scale

0.873

High

376571

EGF
Pro-epidermal growth factor

2

20

Small-scale

0.768

High

1030070

JAK2
Tyrosine-protein kinase JAK2

2

20

Small-scale

0.768

High

1000396

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

20

Small-scale

0.754

High

651515

CBL
E3 ubiquitin-protein ligase CBL

8

20

Small-scale

0.741

High

1030068

EGFR
Epidermal growth factor receptor

1

19

Small-scale

0.724

High

236701

SOCS5
Suppressor of cytokine signaling 5

1

20

Small-scale

0.665

High

699350

VAV
Proto-oncogene vav

1

20

Small-scale

0.647

High

1030071

SOS1
Son of sevenless homolog 1

3

15

Small-scale

0.640

High

59091

ITB4
Integrin beta-4

1

20

Small-scale

0.618

High

267055

OSMR
Oncostatin-M-specific receptor subunit beta

1

20

Small-scale

0.618

High

267118

DOK2
Docking protein 2

1

20

Small-scale

0.618

High

312048

SORL
Sortilin-related receptor

1

20

Small-scale

0.618

High

431341

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

Small-scale

0.618

High

746558

RASK
GTPase KRas

1

20

Small-scale

0.618

High

767011

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

20

Small-scale

0.618

High

777187

PTN12
Tyrosine-protein phosphatase non-receptor type 12

1

20

Small-scale

0.618

High

867747

MK14
Mitogen-activated protein kinase 14

1

14

Small-scale

0.618

High

999820

LRIG1
Leucine-rich repeats and immunoglobulin-like domains protein 1

1

20

Small-scale

0.618

High

1030072

ASPP1
Apoptosis-stimulating of p53 protein 1

1

9

Small-scale

0.618

High

1030074

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

20

High-throughput

0.618

High

1030079

FNDC5
Fibronectin type III domain-containing protein 5

1

1

High-throughput

0.618

High

1030080

LIGO1
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1

1

20

Small-scale

0.618

High

1030081

ARHG7
Rho guanine nucleotide exchange factor 7

1

20

Small-scale

0.618

High

839854

EPS15
Epidermal growth factor receptor substrate 15

2

11

Small-scale

0.571

High

1021149

DAB1
Disabled homolog 1

1

20

Small-scale

0.561

High

205314

AP1B1
AP-1 complex subunit beta-1

1

15

Small-scale

0.479

High

236574

ITB3
Integrin beta-3

1

20

Small-scale

0.479

High

604455

AP2A1
AP-2 complex subunit alpha-1

1

13

Small-scale

0.479

High

1030075

FACD2
Fanconi anemia group D2 protein homolog

1

8

High-throughput

0.479

High

1030076

WDTC1
WD and tetratricopeptide repeats protein 1

1

16

High-throughput

0.479

High

1030077

CBAR1
CBY1-interacting BAR domain-containing protein 1

1

1

High-throughput

0.479

High

1030082

HIP1R
Huntingtin-interacting protein 1-related protein

1

13

Small-scale

0.479

High

398353

CFAD
Complement factor D

1

14

High-throughput

0.437

High

989683

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

8

High-throughput

0.437

High

1030078

TTC23
Tetratricopeptide repeat protein 23

1

1

High-throughput

0.437

High

1030073

TEDC2
Tubulin epsilon and delta complex protein 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025