HitPredict

Interactor 1: INSR (P06213)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Interactor 2: COPD (P48444)
Coatomer subunit delta (Archain) (Delta-coat protein) (Delta-COP)
Gene: ARCN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1382 Hs			1 511
+	Rn
		1146015 T2CB11_RAT (1-1382): 0: 1538: 94.87		COPD_RAT (1-511): 0: 828: 98.83
+	Rn
		544885 INSR_RAT (1-1382): 0: 1527: 94.44		COPD_RAT (1-511): 0: 828: 98.83
+	Hs
		818906 EPHA5_HUMAN (567-1319): 1.23e-176: 555: 20.98		COPD_HUMAN (1-511): 0: 828: 100.00
+	Hs
		818944 EPHA7_HUMAN (562-1356): 4.76e-172: 541: 19.48		COPD_HUMAN (1-511): 0: 828: 100.00
+	Hs
		665450 EPHA8_HUMAN (644-1322): 3.66e-168: 531: 20.68		COPD_HUMAN (1-511): 0: 828: 100.00
+	Hs
		445830 ROS1_HUMAN (511-1377): 3.38e-158: 530: 22.63		COPD_HUMAN (1-511): 0: 828: 100.00
+	Hs
		819048 ALK_HUMAN (982-1339): 1.96e-70: 263: 40.53		COPD_HUMAN (1-511): 0: 828: 100.00
+	Hs
		169166 MUSK_HUMAN (1017-1291): 1.24e-69: 254: 42.22		COPD_HUMAN (1-511): 0: 828: 100.00
+	Hs
		384466 NTRK1_HUMAN (996-1286): 9.16e-68: 247: 42.62		COPD_HUMAN (1-511): 0: 828: 100.00
+	Hs
		818949 NTRK3_HUMAN (996-1290): 1.93e-64: 238: 39.43		COPD_HUMAN (1-511): 0: 828: 100.00