Protein: EFNMT
eEF1A lysine and N-terminal methyltransferase (eEF1A-KNMT) (Methyltransferase-like protein 13) [Includes: eEF1A lysine methyltransferase (EC 2.1.1.-); eEF1A N-terminal methyltransferase (EC 2.1.1.-)]

Gene: EFNMT, METTL13
Organism: Homo sapiens
Interactions: 65
UniProt ID: Q8N6R0

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0016279 - protein-lysine N-methyltransferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1329651

KLK5
Kallikrein-5

3

1

High-throughput

0.667

High

874818

SPB4
Serpin B4

3

1

High-throughput

0.662

High

675082

TNR6
Tumor necrosis factor receptor superfamily member 6

3

0

High-throughput

0.638

High

1329646

THAP1
THAP domain-containing protein 1

3

0

High-throughput

0.633

High

1329637

EFMT3
EEF1A lysine methyltransferase 3

2

1

High-throughput

0.611

High

1090789

TRAF2
TNF receptor-associated factor 2

2

1

High-throughput

0.606

High

372581

MYC
Myc proto-oncogene protein

2

3

High-throughput

0.601

High

478119

SNRPA
U1 small nuclear ribonucleoprotein A

1

1

High-throughput

0.573

High

1323297

VPS52
Vacuolar protein sorting-associated protein 52 homolog

1

0

High-throughput

0.549

High

221945

FOXS1
Forkhead box protein S1

1

2

High-throughput

0.536

High

854165

KI67
Proliferation marker protein Ki-67

1

1

High-throughput

0.536

High

1113698

CUL3
Cullin-3

1

5

High-throughput

0.536

High

1161151

MK06
Mitogen-activated protein kinase 6

1

1

High-throughput

0.536

High

384483

CRYAA
Alpha-crystallin A chain

1

1

High-throughput

0.515

High

1289861

Q86V38
Atrophin 1

1

1

High-throughput

0.515

High

1329636

KLK6
Kallikrein-6

1

1

High-throughput

0.515

High

1111111

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.513

High

1199802

AGK
Acylglycerol kinase, mitochondrial

1

0

High-throughput

0.513

High

1316611

CDK20
Cyclin-dependent kinase 20

1

0

High-throughput

0.513

High

1324823

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.513

High

1329633

DTWD2
tRNA-uridine aminocarboxypropyltransferase 2

1

0

High-throughput

0.513

High

508280

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

2

High-throughput

0.501

High

182662

GP182
G-protein coupled receptor 182

1

1

High-throughput

0.489

High

231329

EFNA2
Ephrin-A2

1

1

High-throughput

0.489

High

1248484

TMCO3
Transmembrane and coiled-coil domain-containing protein 3

1

1

High-throughput

0.489

High

1329652

GPR45
Probable G-protein coupled receptor 45

1

1

High-throughput

0.489

High

174558

TRI66
Tripartite motif-containing protein 66

1

3

High-throughput

0.479

High

342254

BRD1
Bromodomain-containing protein 1

1

1

High-throughput

0.479

High

385972

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

1

High-throughput

0.479

High

401143

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

412257

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.479

High

520204

ANDR
Androgen receptor

1

3

High-throughput

0.479

High

695944

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

913541

KIF11
Kinesin-like protein KIF11

1

1

High-throughput

0.479

High

1100121

TIF1B
Transcription intermediary factor 1-beta

1

2

High-throughput

0.479

High

1137856

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.479

High

1254645

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.479

High

1276485

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.479

High

1329642

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

1

High-throughput

0.479

High

1329644

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.479

High

1329645

BRD7
Bromodomain-containing protein 7

1

2

High-throughput

0.479

High

1329649

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

346071

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

831067

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

1095712

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

0

High-throughput

0.458

High

1178250

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1329638

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1329640

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1329643

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

1227061

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.445

High

914452

EFNB2
Ephrin-B2

1

1

High-throughput

0.437

High

1209387

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

568071

HLAE
HLA class I histocompatibility antigen, alpha chain E

3

0

High-throughput

0.347

High

188595

SIGL5
Sialic acid-binding Ig-like lectin 5

2

0

High-throughput

0.328

High

1329635

TB22A
TBC1 domain family member 22A

2

0

High-throughput

0.318

High

1329639

F167A
Protein FAM167A

2

0

High-throughput

0.313

High

749235

CD70
CD70 antigen

1

0

High-throughput

0.279

Low

771174

APJ
Apelin receptor

1

0

High-throughput

0.279

Low

1329634

F174A
Membrane protein FAM174A

1

0

High-throughput

0.279

Low

1329641

OPALI
Opalin

1

0

High-throughput

0.279

Low

1329647

CCG4
Voltage-dependent calcium channel gamma-4 subunit

1

0

High-throughput

0.279

Low

1329650

LAMP3
Lysosome-associated membrane glycoprotein 3

1

0

High-throughput

0.279

Low

879271

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

888469

TSP3
Thrombospondin-3

1

0

High-throughput

0.249

Low

1329648

SL9A2
Sodium/hydrogen exchanger 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025