Interactor 1: INSR (P06213)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Interactor 2: WNT3A (P56704)
Protein Wnt-3a
Gene: WNT3A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.536

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001934 - positive regulation of protein phosphorylation
GO:0002092 - positive regulation of receptor internalization
GO:0005886 - plasma membrane
GO:0008284 - positive regulation of cell population proliferation
GO:0019904 - protein domain specific binding
and 2 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 1382
Hs

1 352
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm

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Last updated: 15 Jul 2024