HitPredict

Interactor 1: LCK (P06239)
Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)
Gene: LCK

Interactor 2: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr, PH~SH3_1
Common GO terms	GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 509 Hs			1 1025
+	Hs
		411800 LCK_HUMAN (1-509): 0: 661: 100.00		DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61
+	Hs
		411764 LCK_HUMAN (1-509): 0: 661: 100.00		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		411861 LCK_HUMAN (1-509): 0: 661: 100.00		PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24
+	Hs
		411897 LCK_HUMAN (1-509): 0: 661: 100.00		PKHA6_HUMAN (356-581): 1.69e-31: 135: 24.49
+	Hs
		433909 LYN_HUMAN (1-509): 0: 582: 62.72		DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61
+	Hs
		433831 LYN_HUMAN (1-509): 0: 582: 62.72		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		433388 YES_HUMAN (26-507): 0: 581: 58.06		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		434015 LYN_HUMAN (1-509): 0: 582: 62.72		PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24
+	Hs
		412058 FYN_HUMAN (30-507): 0: 586: 59.01		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		433620 LYN_HUMAN (1-509): 0: 582: 62.72		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		111443 J3QRU1_HUMAN (26-507): 0: 581: 58.06		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		433272 YES_HUMAN (26-507): 0: 581: 58.06		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		724720 BLK_HUMAN (1-509): 0: 557: 59.35		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66