Protein: DPOD1
DNA polymerase delta catalytic subunit (EC 2.7.7.7) (3'-5' exodeoxyribonuclease) (EC 3.1.11.-) (DNA polymerase subunit delta p125)

Gene: DPOD1, POLD1
Organism: Homo sapiens
Interactions: 205
UniProt ID: P28340

Gene Ontology (top 5):
GO:0000109 - nucleotide-excision repair complex
GO:0000166 - nucleotide binding
GO:0000731 - DNA synthesis involved in DNA repair
GO:0003677 - DNA binding
GO:0003682 - chromatin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

517071

PCNA
Proliferating cell nuclear antigen

10

9

Small-scale

0.974

High

658332

DPOD2
DNA polymerase delta subunit 2

7

6

Small-scale

0.966

High

658441

DPOD4
DNA polymerase delta subunit 4

5

1

Small-scale

0.725

High

658368

DPOD3
DNA polymerase delta subunit 3

5

0

Small-scale

0.682

High

658417

MMS19
MMS19 nucleotide excision repair protein homolog

4

3

Small-scale

0.678

High

346002

MYC
Myc proto-oncogene protein

3

2

High-throughput

0.656

High

658457

CIA2B
Cytosolic iron-sulfur assembly component 2B

3

3

Small-scale

0.643

High

658445

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

2

1

High-throughput

0.628

High

282826

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

4

4

Small-scale

0.613

High

658362

CUL3
Cullin-3

2

3

High-throughput

0.611

High

658416

WRIP1
ATPase WRNIP1

2

1

Small-scale

0.611

High

226598

PRKN
E3 ubiquitin-protein ligase parkin

2

5

High-throughput

0.584

High

658449

ZRAN1
Ubiquitin thioesterase ZRANB1

2

1

High-throughput

0.584

High

658365

LASP1
LIM and SH3 domain protein 1

2

0

High-throughput

0.580

High

625137

CDK2
Cyclin-dependent kinase 2

1

5

Small-scale

0.578

High

369036

ESR1
Estrogen receptor

2

4

High-throughput

0.571

High

373730

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

2

High-throughput

0.571

High

408559

KPCB
Protein kinase C beta type

2

1

High-throughput

0.571

High

658351

KPCZ
Protein kinase C zeta type

2

1

High-throughput

0.571

High

414181

RB
Retinoblastoma-associated protein

1

1

Small-scale

0.561

High

624543

CCNE1
G1/S-specific cyclin-E1

1

4

Small-scale

0.561

High

658404

CSN5
COP9 signalosome complex subunit 5

2

0

High-throughput

0.559

High

658433

SPRTN
DNA-dependent metalloprotease SPRTN

2

0

Small-scale

0.559

High

149822

RFXK
DNA-binding protein RFXANK

1

3

High-throughput

0.536

High

311668

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

2

High-throughput

0.536

High

323603

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.536

High

658349

PPARD
Peroxisome proliferator-activated receptor delta

1

2

High-throughput

0.536

High

658360

SNW1
SNW domain-containing protein 1

1

1

High-throughput

0.536

High

658370

SF3B3
Splicing factor 3B subunit 3

1

2

High-throughput

0.536

High

658372

MK06
Mitogen-activated protein kinase 6

1

4

High-throughput

0.536

High

658407

EFMT3
EEF1A lysine methyltransferase 3

1

1

High-throughput

0.536

High

658421

NPAS1
Neuronal PAS domain-containing protein 1

1

1

High-throughput

0.536

High

658431

UBXN6
UBX domain-containing protein 6

1

1

High-throughput

0.536

High

658436

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

3

High-throughput

0.536

High

658443

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

1

High-throughput

0.536

High

658451

HSPB8
Heat shock protein beta-8

1

2

High-throughput

0.536

High

260521

TP4A3
Protein tyrosine phosphatase type IVA 3

1

2

High-throughput

0.515

High

658325

CCNF
Cyclin-F

1

6

High-throughput

0.515

High

280357

GLRX3
Glutaredoxin-3

1

0

High-throughput

0.513

High

380741

S100B
Protein S100-B

1

0

High-throughput

0.513

High

428033

TBB5
Tubulin beta chain

1

0

High-throughput

0.513

High

515805

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.513

High

658330

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.513

High

658379

OTU1
Ubiquitin thioesterase OTU1

1

0

High-throughput

0.513

High

658383

CRTC3
CREB-regulated transcription coactivator 3

1

0

High-throughput

0.513

High

658387

UBP43
Ubiquitin carboxyl-terminal hydrolase 43

1

0

High-throughput

0.513

High

658390

MTA70
N6-adenosine-methyltransferase catalytic subunit

1

0

High-throughput

0.513

High

658391

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

658406

FBXW5
F-box/WD repeat-containing protein 5

1

0

High-throughput

0.513

High

658412

HES6
Transcription cofactor HES-6

1

0

High-throughput

0.513

High

658418

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.513

High

658446

CNOT2
CCR4-NOT transcription complex subunit 2

1

0

High-throughput

0.513

High

515338

CDK4
Cyclin-dependent kinase 4

1

6

Small-scale

0.501

High

658316

CCND3
G1/S-specific cyclin-D3

1

6

Small-scale

0.501

High

658341

SUMO2
Small ubiquitin-related modifier 2

1

2

High-throughput

0.501

High

658425

SLD5
DNA replication complex GINS protein SLD5

1

7

Small-scale

0.501

High

658375

KLH12
Kelch-like protein 12

1

0

High-throughput

0.493

High

276228

CIB2
Calcium and integrin-binding family member 2

1

1

High-throughput

0.489

High

658315

CD6
T-cell differentiation antigen CD6

1

1

High-throughput

0.489

High

658376

ANR39
Ankyrin repeat domain-containing protein 39

1

2

High-throughput

0.489

High

658392

KLH34
Kelch-like protein 34

1

1

High-throughput

0.489

High

658432

DNAI2
Dynein axonemal intermediate chain 2

1

2

High-throughput

0.489

High

658452

PSG11
Pregnancy-specific beta-1-glycoprotein 11

1

1

High-throughput

0.489

High

658430

TRI55
Tripartite motif-containing protein 55

1

6

High-throughput

0.481

High

150866

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

1

High-throughput

0.479

High

162423

XPO1
Exportin-1

1

2

High-throughput

0.479

High

243302

DNJA2
DnaJ homolog subfamily A member 2

1

2

High-throughput

0.479

High

243978

BRD4
Bromodomain-containing protein 4

1

3

High-throughput

0.479

High

304036

UBR5
E3 ubiquitin-protein ligase UBR5

1

1

Small-scale

0.479

High

319128

BRD1
Bromodomain-containing protein 1

1

3

High-throughput

0.479

High

322218

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

3

High-throughput

0.479

High

337357

ABL1
Tyrosine-protein kinase ABL1

1

2

High-throughput

0.479

High

386150

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

388246

HSPB1
Heat shock protein beta-1

1

2

High-throughput

0.479

High

393054

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

1

High-throughput

0.479

High

412034

FYN
Tyrosine-protein kinase Fyn

1

2

High-throughput

0.479

High

487158

ANDR
Androgen receptor

1

4

High-throughput

0.479

High

503495

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

522799

SRC
Proto-oncogene tyrosine-protein kinase Src

1

2

High-throughput

0.479

High

552008

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

561504

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

1

High-throughput

0.479

High

569237

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

573138

TCPA
T-complex protein 1 subunit alpha

1

2

High-throughput

0.479

High

650434

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

658317

1433B
14-3-3 protein beta/alpha

1

1

High-throughput

0.479

High

658318

1433S
14-3-3 protein sigma

1

1

High-throughput

0.479

High

658319

STIP1
Stress-induced-phosphoprotein 1

1

4

High-throughput

0.479

High

658320

MCM7
DNA replication licensing factor MCM7

1

10

High-throughput

0.479

High

658322

PHB1
Prohibitin 1

1

1

High-throughput

0.479

High

658323

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.479

High

658324

BRCA1
Breast cancer type 1 susceptibility protein

1

3

High-throughput

0.479

High

658328

MAGA6
Melanoma-associated antigen 6

1

1

High-throughput

0.479

High

658329

ATRX
Transcriptional regulator ATRX

1

4

High-throughput

0.479

High

658331

TCPE
T-complex protein 1 subunit epsilon

1

3

High-throughput

0.479

High

658333

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.479

High

658334

TCPG
T-complex protein 1 subunit gamma

1

3

High-throughput

0.479

High

658335

TCPQ
T-complex protein 1 subunit theta

1

4

High-throughput

0.479

High

658336

TCPD
T-complex protein 1 subunit delta

1

2

High-throughput

0.479

High

658338

CTBP2
C-terminal-binding protein 2

1

1

High-throughput

0.479

High

658344

H2B1C
Histone H2B type 1-C/E/F/G/I

1

6

High-throughput

0.479

High

658345

GRB2
Growth factor receptor-bound protein 2

1

3

High-throughput

0.479

High

658346

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

1

High-throughput

0.479

High

658347

PRKDC
DNA-dependent protein kinase catalytic subunit

1

2

High-throughput

0.479

High

658348

RED1
Double-stranded RNA-specific editase 1

1

3

High-throughput

0.479

High

658350

ERCC6
DNA excision repair protein ERCC-6

1

3

Small-scale

0.479

High

658352

RAD51
DNA repair protein RAD51 homolog 1

1

1

Small-scale

0.479

High

658353

DHX9
ATP-dependent RNA helicase A

1

1

Small-scale

0.479

High

658354

ERCC8
DNA excision repair protein ERCC-8

1

2

High-throughput

0.479

High

658355

TIF1B
Transcription intermediary factor 1-beta

1

3

High-throughput

0.479

High

658357

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

5

High-throughput

0.479

High

658361

CUL1
Cullin-1

1

3

High-throughput

0.479

High

658363

CUL4B
Cullin-4B

1

3

High-throughput

0.479

High

658367

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

658369

PCBP1
Poly(rC)-binding protein 1

1

1

High-throughput

0.479

High

658371

TERF2
Telomeric repeat-binding factor 2

1

1

High-throughput

0.479

High

658374

CL16A
Protein CLEC16A

1

1

High-throughput

0.479

High

658380

A16L1
Autophagy-related protein 16-1

1

4

High-throughput

0.479

High

658389

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.479

High

658396

NUP43
Nucleoporin Nup43

1

3

High-throughput

0.479

High

658397

COP1
E3 ubiquitin-protein ligase COP1

1

2

High-throughput

0.479

High

658400

HS105
Heat shock protein 105 kDa

1

6

High-throughput

0.479

High

658401

ESR2
Estrogen receptor beta

1

4

High-throughput

0.479

High

658402

KAT6A
Histone acetyltransferase KAT6A

1

2

High-throughput

0.479

High

658403

RENT1
Regulator of nonsense transcripts 1

1

2

Small-scale

0.479

High

658409

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

3

High-throughput

0.479

High

658410

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

1

High-throughput

0.479

High

658415

CIC
Protein capicua homolog

1

2

High-throughput

0.479

High

658419

RING2
E3 ubiquitin-protein ligase RING2

1

4

High-throughput

0.479

High

658420

DNJC7
DnaJ homolog subfamily C member 7

1

4

High-throughput

0.479

High

658423

E2AK1
Eukaryotic translation initiation factor 2-alpha kinase 1

1

2

High-throughput

0.479

High

658429

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

4

Small-scale

0.479

High

658437

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

658444

MTMR4
Myotubularin-related protein 4

1

1

High-throughput

0.479

High

658448

POLK
DNA polymerase kappa

1

4

Small-scale

0.479

High

658450

DDX20
Probable ATP-dependent RNA helicase DDX20

1

1

High-throughput

0.479

High

658453

RUVB2
RuvB-like 2

1

1

High-throughput

0.479

High

658459

ARI1
E3 ubiquitin-protein ligase ARIH1

1

3

High-throughput

0.479

High

658340

YPEL3
Protein yippee-like 3

1

0

High-throughput

0.460

High

658394

MCPH1
Microcephalin

1

0

Small-scale

0.460

High

119921

AP3B1
AP-3 complex subunit beta-1

1

0

High-throughput

0.458

High

241982

PAGE4
P antigen family member 4

1

0

High-throughput

0.458

High

255533

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.458

High

298187

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

373352

CATA
Catalase

1

0

High-throughput

0.458

High

390077

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

527953

RINI
Ribonuclease inhibitor

1

0

High-throughput

0.458

High

560380

MGMT
Methylated-DNA--protein-cysteine methyltransferase

1

0

Small-scale

0.458

High

571320

DDX5
Probable ATP-dependent RNA helicase DDX5

1

0

High-throughput

0.458

High

579662

XRCC1
DNA repair protein XRCC1

1

0

Small-scale

0.458

High

653169

PYR1
Multifunctional protein CAD

1

0

High-throughput

0.458

High

658327

MATR3
Matrin-3

1

0

High-throughput

0.458

High

658337

MFAP1
Microfibrillar-associated protein 1

1

0

High-throughput

0.458

High

658339

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

0

High-throughput

0.458

High

658342

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

658343

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.458

High

658358

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

658364

MDC1
Mediator of DNA damage checkpoint protein 1

1

0

High-throughput

0.458

High

658366

NOLC1
Nucleolar and coiled-body phosphoprotein 1

1

0

High-throughput

0.458

High

658378

DCA12
DDB1- and CUL4-associated factor 12

1

0

High-throughput

0.458

High

658382

ZN746
Zinc finger protein 746

1

0

High-throughput

0.458

High

658388

CSN6
COP9 signalosome complex subunit 6

1

0

High-throughput

0.458

High

658395

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

658399

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

658413

EAF1
ELL-associated factor 1

1

0

High-throughput

0.458

High

658414

RBM14
RNA-binding protein 14

1

0

High-throughput

0.458

High

658422

CND3
Condensin complex subunit 3

1

0

Small-scale

0.458

High

658424

RIOK1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

658426

RN126
E3 ubiquitin-protein ligase RNF126

1

0

High-throughput

0.458

High

658428

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

658438

RENT2
Regulator of nonsense transcripts 2

1

0

Small-scale

0.458

High

658439

PIDD1
p53-induced death domain-containing protein 1

1

0

Small-scale

0.458

High

658442

GFOD1
Glucose-fructose oxidoreductase domain-containing protein 1

1

0

High-throughput

0.458

High

658454

NUDC
Nuclear migration protein nudC

1

0

High-throughput

0.458

High

658455

SYFA
Phenylalanine--tRNA ligase alpha subunit

1

0

High-throughput

0.458

High

658456

GSTK1
Glutathione S-transferase kappa 1

1

0

High-throughput

0.458

High

658458

RTCB
RNA-splicing ligase RtcB homolog

1

0

High-throughput

0.458

High

256942

KDM4A
Lysine-specific demethylase 4A

1

3

Small-scale

0.445

High

264174

CDC45
Cell division control protein 45 homolog

1

4

Small-scale

0.445

High

658321

BMI1
Polycomb complex protein BMI-1

1

2

High-throughput

0.445

High

658377

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

4

High-throughput

0.445

High

658398

CE192
Centrosomal protein of 192 kDa

1

1

High-throughput

0.445

High

384321

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.437

High

658386

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

658411

PGAM5
Serine/threonine-protein phosphatase PGAM5, mitochondrial

1

1

High-throughput

0.437

High

658435

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.437

High

658440

Q9HCK3
KIAA1569 protein

1

1

High-throughput

0.437

High

658405

IRF7
Interferon regulatory factor 7

1

0

High-throughput

0.426

High

658359

ATR
Serine/threonine-protein kinase ATR

1

2

Small-scale

0.408

High

658385

PKHG7
Pleckstrin homology domain-containing family G member 7

1

1

High-throughput

0.407

High

658384

ATL4
ADAMTS-like protein 4

2

0

High-throughput

0.316

High

393772

SCG1
Secretogranin-1

1

0

High-throughput

0.282

High

658447

CE126
Centrosomal protein of 126 kDa

1

0

High-throughput

0.282

High

179146

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.279

Low

522591

MYH7
Myosin-7

1

0

High-throughput

0.279

Low

645956

CRBB3
Beta-crystallin B3

1

0

High-throughput

0.279

Low

658356

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

1

0

High-throughput

0.279

Low

658373

INF2
Inverted formin-2

1

0

High-throughput

0.279

Low

658393

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

658408

ARRD3
Arrestin domain-containing protein 3

1

0

High-throughput

0.279

Low

658434

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

66992

CRTP1
Cysteine-rich tail protein 1

1

0

High-throughput

0.268

Low

658326

RHG25
Rho GTPase-activating protein 25

1

0

High-throughput

0.249

Low

658381

GRAM4
GRAM domain-containing protein 4

1

0

Small-scale

0.249

Low

658427

LRC61
Leucine-rich repeat-containing protein 61

1

0

High-throughput

0.249

Low

596500

CD3Z
T-cell surface glycoprotein CD3 zeta chain

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024