HitPredict

Interactor 1: FYN (P06241)
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)
Gene: FYN

Interactor 2: ENPL (P14625)
Endoplasmin (94 kDa glucose-regulated protein) (GRP-94) (Heat shock protein 90 kDa beta member 1) (Heat shock protein family C member 4) (Tumor rejection antigen 1) (gp96 homolog)
Gene: HSP90B1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 537 Hs			1 803
+	Hs
		411949 FYN_HUMAN (1-537): 0: 643: 100.00		HS90B_HUMAN (75-783): 0: 997: 46.54
+	Hs
		411945 FYN_HUMAN (1-537): 0: 643: 100.00		HS90A_HUMAN (60-783): 0: 990: 45.34
+	Hs
		433552 LYN_HUMAN (1-535): 0: 535: 54.48		ENPL_HUMAN (1-803): 0: 1073: 100.00
+	Hs
		437847 SRC_HUMAN (1-537): 0: 598: 68.21		HS90B_HUMAN (75-783): 0: 997: 46.54
+	Hs
		431481 SRC_HUMAN (1-537): 0: 598: 68.21		HS90A_HUMAN (60-783): 0: 990: 45.34
+	Hs
		433218 YES_HUMAN (1-537): 0: 591: 71.61		HS90B_HUMAN (75-783): 0: 997: 46.54
+	Hs
		431433 YES_HUMAN (1-537): 0: 591: 71.61		HS90A_HUMAN (60-783): 0: 990: 45.34
+	Hs
		437823 FGR_HUMAN (1-536): 0: 581: 69.82		HS90B_HUMAN (75-783): 0: 997: 46.54
+	Hs
		431451 FGR_HUMAN (1-536): 0: 581: 69.82		HS90A_HUMAN (60-783): 0: 990: 45.34
+	Hs
		411556 LCK_HUMAN (40-535): 0: 551: 57.60		HS90B_HUMAN (75-783): 0: 997: 46.54
+	Hs
		437817 HCK_HUMAN (1-535): 0: 548: 56.64		HS90B_HUMAN (75-783): 0: 997: 46.54
+	Hs
		411551 LCK_HUMAN (40-535): 0: 551: 57.60		HS90A_HUMAN (60-783): 0: 990: 45.34
+	Hs
		431445 HCK_HUMAN (1-535): 0: 548: 56.64		HS90A_HUMAN (60-783): 0: 990: 45.34
+	Hs
		433526 LYN_HUMAN (1-535): 0: 535: 54.48		HS90B_HUMAN (75-783): 0: 997: 46.54
+	Rn
		948934 LYN_RAT (1-535): 0: 538: 54.10		HS90A_RAT (60-783): 0: 988: 45.28
+	Hs
		431434 LYN_HUMAN (1-535): 0: 535: 54.48		HS90A_HUMAN (60-783): 0: 990: 45.34
+	Dm
		365472 SRC42_DROME (35-535): 0: 538: 55.25		HSP83_DROME (69-783): 0: 981: 45.74
+	Hs
		437966 ABL2_HUMAN (7-537): 2.06e-170: 515: 38.09		HS90B_HUMAN (75-783): 0: 997: 46.54
+	Hs
		431626 ABL2_HUMAN (7-537): 2.06e-170: 515: 38.09		HS90A_HUMAN (60-783): 0: 990: 45.34
+	Hs
		431666 BLK_HUMAN (28-532): 2.42e-179: 515: 56.72		HS90A_HUMAN (60-783): 0: 990: 45.34