HitPredict

Interactor 1: KAPB (P06245)
cAMP-dependent protein kinase type 2 (PKA 2) (EC 2.7.11.11)
Gene: TPK2

Interactor 2: KAPR (P07278)
cAMP-dependent protein kinase regulatory subunit (cAPK regulatory subunit) (Bypass of cyclase mutations protein 1) (Protein kinase A regulatory subunit) (PKA regulatory subunit)
Gene: BCY1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.988

The method score is based on:

Property Details
Experiments 8386630, 11283351, 11805837, 11805826, 21925385, 16554755, 18467557, 33039554, 18719252, 37968396, 9811878, 16429126, 16319894, 17242065, 36167807, 20489023, 21460040, 22957732
Identification Methods genetic interference, experimental interaction detection, two hybrid pooling approach, anti tag coimmunoprecipitation, tandem affinity purification, pull down, affinity chromatography technology, protein complementation assay, two hybrid, enzymatic study and 1 others

more...
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~cNMP_binding, Pkinase~RIIa
Common GO terms GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005952 - cAMP-dependent protein kinase complex
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 380
Sc

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Last updated: 15 Jul 2024