Interactor 1: DOA (P06340)
HLA class II histocompatibility antigen, DO alpha chain (MHC DN-alpha) (MHC DZ alpha) (MHC class II antigen DOA)
Gene: HLA-DOA

Interactor 2: DOB (P13765)
HLA class II histocompatibility antigen, DO beta chain (MHC class II antigen DOB)
Gene: HLA-DOB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 23222639
Identification Methods molecular sieving
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains C1-set~C1-set, C1-set~MHC_II_beta, C1-set~MHC_II_alpha, MHC_II_alpha~MHC_II_beta
Common GO terms GO:0002250 - adaptive immune response
GO:0002503 - peptide antigen assembly with MHC class II protein complex
GO:0002587 - negative regulation of antigen processing and presentation of peptide antigen via MHC class II
GO:0005765 - lysosomal membrane
GO:0019886 - antigen processing and presentation of exogenous peptide antigen via MHC class II
and 7 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 250
Hs

1 273
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Last updated: 15 Jul 2024