HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: MCM7 (P33993)
DNA replication licensing factor MCM7 (EC 3.6.4.12) (CDC47 homolog) (P1.1-MCM3)
Gene: MCM7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	32807901, 38580884, 37438558
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006974 - DNA damage response GO:0071466 - cellular response to xenobiotic stimulus
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 719
+	Hs
		413291 P53_HUMAN (1-393): 0: 619: 100.00		MCM5_HUMAN (6-716): 0: 682: 27.61
+	Hs
		413411 P53_HUMAN (1-393): 0: 619: 100.00		MCM2_HUMAN (8-690): 0: 643: 28.13
+	Hs
		413290 P53_HUMAN (1-393): 0: 619: 100.00		MCM4_HUMAN (5-700): 0: 636: 31.52
+	Hs
		413827 P53_HUMAN (1-393): 0: 619: 100.00		MCM6_HUMAN (3-715): 0: 623: 28.05