HitPredict

Interactor 1: RB (P06400)
Retinoblastoma-associated protein (p105-Rb) (p110-RB1) (pRb) (Rb) (pp110)
Gene: RB1

Interactor 2: CEBPD (P49716)
CCAAT/enhancer-binding protein delta (C/EBP delta) (Nuclear factor NF-IL6-beta) (NF-IL6-beta)
Gene: CEBPD

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	15674331, 20971808
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006366 - transcription by RNA polymerase II GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 928 Hs			1 269
+	Mm
		527148 RB_MOUSE (24-928): 0: 1260: 91.38		CEBPD_MOUSE (1-269): 1.08e-78: 240: 85.87
+	Hs
		414297 RB_HUMAN (1-928): 0: 1323: 100.00		CEBPE_HUMAN (14-264): 4.08e-53: 175: 35.21
+	Hs
		414212 RB_HUMAN (1-928): 0: 1323: 100.00		CEBPA_HUMAN (16-265): 1.09e-45: 158: 26.67
+	Hs
		401261 RB_HUMAN (1-928): 0: 1323: 100.00		JUN_HUMAN (37-254): 1.5e-38: 139: 16.18
+	Hs
		414159 RB_HUMAN (1-928): 0: 1323: 100.00		CEBPB_HUMAN (161-265): 5.26e-31: 119: 53.33
+	Hs
		414152 RB_HUMAN (1-928): 0: 1323: 100.00		ATF2_HUMAN (81-261): 6.9e-26: 107: 19.43
+	Mm
		527139 RB_MOUSE (24-928): 0: 1260: 91.38		CEBPA_MOUSE (16-265): 2.4e-42: 150: 26.39
+	Rn
		645770 RB_RAT (1-928): 0: 1274: 88.90		CEBPG_RAT (136-256): 2.11e-26: 102: 33.88
+	Mm
		527132 RB_MOUSE (24-928): 0: 1260: 91.38		CEBPB_MOUSE (186-265): 1.75e-27: 109: 62.50
+	Mm
		862832 RBL1_MOUSE (594-879): 2.53e-78: 278: 29.52		CEBPA_MOUSE (16-265): 2.4e-42: 150: 26.39