Interactor 1: RB (P06400)
Retinoblastoma-associated protein (p105-Rb) (p110-RB1) (pRb) (Rb) (pp110)
Gene: RB1
Interactor 2: E2F2 (Q14209)
Transcription factor E2F2 (E2F-2)
Gene: E2F2
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.972 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24981860, 12502741, 8657117, 8246996, 31130363, 17380128, 7739537, 16360038 |
| Identification Methods | affinity chromatography technology, x-ray crystallography, pull down, comigration in non denaturing gel electrophoresis, coimmunoprecipitation, isothermal titration calorimetry, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | E2F_CC-MB~Rb_C |
| Common GO terms | GO:0000785 - chromatin GO:0005654 - nucleoplasm GO:0006355 - regulation of DNA-templated transcription GO:0035189 - Rb-E2F complex GO:0045944 - positive regulation of transcription by RNA polymerase II and 1 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
