HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: MAGBI (Q96M61)
Melanoma-associated antigen B18 (MAGE-B18 antigen)
Gene: MAGEB18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.666

Property	Details
Experiments	16189514, 16713569, 31515488
Identification Methods	two hybrid, two hybrid pooling approach, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 343
+	Hs
		413361 P53_HUMAN (1-393): 0: 619: 100.00		MAGA1_HUMAN (1-301): 5.25e-133: 382: 42.38
+	Hs
		413362 P53_HUMAN (1-393): 0: 619: 100.00		MAGA2_HUMAN (1-312): 2.5e-132: 381: 40.13
+	Hs
		414765 P53_HUMAN (1-393): 0: 619: 100.00		MAGC2_HUMAN (94-343): 1.85e-117: 345: 48.00
+	Hs
		191511 P53_HUMAN (1-393): 0: 619: 100.00		MAGB2_HUMAN (1-312): 1.27e-117: 344: 50.32
+	Hs
		414852 P53_HUMAN (1-393): 0: 619: 100.00		MAGD2_HUMAN (9-307): 1.62e-102: 315: 30.92
+	Hs
		414482 P53_HUMAN (1-393): 0: 619: 100.00		NECD_HUMAN (20-324): 2.84e-95: 287: 29.52
+	Mm
		382450 P53_MOUSE (1-393): 0: 589: 77.35		NECD_MOUSE (4-332): 1.22e-94: 286: 29.79
+	Hs
		186714 P73_HUMAN (13-362): 2.36e-166: 481: 39.74		MAGA2_HUMAN (1-312): 2.5e-132: 381: 40.13