HitPredict

Interactor 1: CDK1 (P06493)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)
Gene: CDK1

Interactor 2: CCNB1 (P14635)
G2/mitotic-specific cyclin-B1
Gene: CCNB1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.99 1.00 0.996

The method score is based on:

Property Details
Experiments 9560267, 24508230, 26496610, 25750436, 27030811, 9891079, 2570636, 30674583, 17679094, 34224728, 20360007, 35271311, 16784539, 16024801, 27402161, 21924351, 17242184, 15554878, 16159883, 20228808 and 35 others

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Identification Methods affinity chromatography technology, enzymatic study, biochemical, pull down, anti tag coimmunoprecipitation, coimmunoprecipitation, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cyclin_C~Pkinase, Cyclin_N~Pkinase
Common GO terms GO:0000086 - G2/M transition of mitotic cell cycle
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005759 - mitochondrial matrix
and 7 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 297
Hs

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Last updated: 15 Jul 2024