HitPredict

Interactor 1: CDK1 (P06493)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)
Gene: CDK1

Interactor 2: RFA2 (P15927)
Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)
Gene: RPA2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	25113031, 10336450, 20679368, 37827155
Identification Methods	enzymatic study, affinity chromatography technology, proximity labelling technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006260 - DNA replication
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 297 Hs			1 270
+	Hs
		551975 CDK2_HUMAN (1-297): 3.26e-149: 421: 65.32		RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00
+	Hs
		552508 CDK5_HUMAN (1-293): 1.55e-134: 384: 56.12		RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00
+	Hs
		414898 CDK1_HUMAN (1-297): 2.82e-143: 406: 100.00		RFA4_HUMAN (1-268): 6.87e-96: 283: 45.56
+	Ca
		793056 CDK1_CANAL (1-287): 3.35e-132: 379: 63.67		Q59Z33_CANAL (4-264): 1.49e-64: 204: 26.37