Protein: SRBS2
Sorbin and SH3 domain-containing protein 2 (Arg-binding protein 2) (ArgBP2) (Arg/Abl-interacting protein 2) (Sorbin)

Gene: SRBS2, SORBS2
Organism: Homo sapiens
Interactions: 82
UniProt ID: O94875

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005200 - structural constituent of cytoskeleton
GO:0005634 - nucleus
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

199493

EFS
Embryonal Fyn-associated substrate

3

20

High-throughput

0.871

High

298942

SRBS2
Sorbin and SH3 domain-containing protein 2

3

17

High-throughput

0.861

High

298944

ABL1
Tyrosine-protein kinase ABL1

3

20

Small-scale

0.847

High

298945

EGFR
Epidermal growth factor receptor

2

20

Small-scale

0.785

High

146666

SOCS7
Suppressor of cytokine signaling 7

2

20

High-throughput

0.783

High

298987

ABI1
Abl interactor 1

2

19

High-throughput

0.783

High

208967

NCK2
Cytoplasmic protein NCK2

1

19

High-throughput

0.740

High

298979

FAK2
Protein-tyrosine kinase 2-beta

1

20

Small-scale

0.724

High

298959

ABL2
Tyrosine-protein kinase ABL2

1

20

Small-scale

0.709

High

298999

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

20

High-throughput

0.698

High

298967

1433E
14-3-3 protein epsilon

3

9

High-throughput

0.676

High

298968

1433Z
14-3-3 protein zeta/delta

3

20

High-throughput

0.665

High

299002

SH24A
SH2 domain-containing protein 4A

1

20

High-throughput

0.662

High

299006

DLGP4
Disks large-associated protein 4

3

20

Small-scale

0.658

High

298952

1433B
14-3-3 protein beta/alpha

2

20

High-throughput

0.635

High

298949

CBL
E3 ubiquitin-protein ligase CBL

2

20

Small-scale

0.631

High

298951

AKT2
RAC-beta serine/threonine-protein kinase

1

10

High-throughput

0.621

High

298986

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

18

High-throughput

0.621

High

298991

WASF1
Actin-binding protein WASF1

2

20

Small-scale

0.620

High

148235

CTRO
Citron Rho-interacting kinase

1

10

High-throughput

0.618

High

299003

ANLN
Anillin

1

12

High-throughput

0.618

High

60544

VP37C
Vacuolar protein sorting-associated protein 37C

3

20

High-throughput

0.616

High

203192

SYNJ1
Synaptojanin-1

2

20

Small-scale

0.614

High

298965

1433G
14-3-3 protein gamma

2

20

High-throughput

0.612

High

126890

WASL
Actin nucleation-promoting factor WASL

2

20

High-throughput

0.606

High

176900

EIF3H
Eukaryotic translation initiation factor 3 subunit H

2

14

High-throughput

0.606

High

298976

CBLB
E3 ubiquitin-protein ligase CBL-B

2

20

High-throughput

0.606

High

298953

1433S
14-3-3 protein sigma

2

20

High-throughput

0.601

High

211443

ACTN4
Alpha-actinin-4

1

20

High-throughput

0.582

High

298946

ACTN1
Alpha-actinin-1

1

20

Small-scale

0.573

High

298990

PALLD
Palladin

1

18

Small-scale

0.573

High

298960

WASP
Actin nucleation-promoting factor WAS

1

20

High-throughput

0.573

High

298973

PTN12
Tyrosine-protein phosphatase non-receptor type 12

1

20

Small-scale

0.561

High

298978

ADA15
Disintegrin and metalloproteinase domain-containing protein 15

1

20

Small-scale

0.561

High

298950

1433T
14-3-3 protein theta

1

20

High-throughput

0.554

High

298972

1433F
14-3-3 protein eta

1

20

High-throughput

0.554

High

298974

GOGA2
Golgin subfamily A member 2

2

20

High-throughput

0.553

High

298996

AP4AT
AP-4 complex accessory subunit Tepsin

2

1

High-throughput

0.553

High

117537

MYO1C
Unconventional myosin-Ic

1

15

High-throughput

0.536

High

298948

FLNA
Filamin-A

1

20

High-throughput

0.536

High

298957

MYH9
Myosin-9

1

9

High-throughput

0.536

High

298961

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

16

High-throughput

0.536

High

298962

CAZA2
F-actin-capping protein subunit alpha-2

1

9

High-throughput

0.536

High

298966

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

14

High-throughput

0.536

High

298969

CLH1
Clathrin heavy chain 1

1

7

High-throughput

0.536

High

298984

DREB
Drebrin

1

20

High-throughput

0.536

High

298988

SYNPO
Synaptopodin

1

20

High-throughput

0.536

High

298992

MY18A
Unconventional myosin-XVIIIa

1

19

High-throughput

0.536

High

298975

PAK2
Serine/threonine-protein kinase PAK 2

1

20

Small-scale

0.515

High

298981

SUZ12
Polycomb protein SUZ12

1

1

High-throughput

0.515

High

298963

NR1H2
Oxysterols receptor LXR-beta

1

14

High-throughput

0.508

High

299000

SEM6A
Semaphorin-6A

1

8

Small-scale

0.508

High

145930

DLGP1
Disks large-associated protein 1

1

20

Small-scale

0.501

High

298947

VINC
Vinculin

1

12

Small-scale

0.501

High

298964

AFAD
Afadin

1

20

Small-scale

0.501

High

298977

ADAM9
Disintegrin and metalloproteinase domain-containing protein 9

1

20

Small-scale

0.501

High

298954

RL9
Large ribosomal subunit protein uL6

1

1

High-throughput

0.481

High

298980

FAT1
Protocadherin Fat 1

1

6

Small-scale

0.481

High

168691

ARC1B
Actin-related protein 2/3 complex subunit 1B

1

10

Small-scale

0.479

High

279377

FLOT1
Flotillin-1

1

7

Small-scale

0.479

High

298943

BAG3
BAG family molecular chaperone regulator 3

1

3

High-throughput

0.479

High

298955

CTNA1
Catenin alpha-1

1

12

High-throughput

0.479

High

298956

CTNB1
Catenin beta-1

1

6

High-throughput

0.479

High

298958

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

14

High-throughput

0.479

High

298982

KIF14
Kinesin-like protein KIF14

1

20

High-throughput

0.479

High

298983

MARE1
Microtubule-associated protein RP/EB family member 1

1

7

High-throughput

0.479

High

298993

HDAC2
Histone deacetylase 2

1

7

High-throughput

0.479

High

298998

LZTS2
Leucine zipper putative tumor suppressor 2

1

20

High-throughput

0.479

High

299001

CHM4B
Charged multivesicular body protein 4b

1

11

High-throughput

0.479

High

299004

ZRAN1
Ubiquitin thioesterase ZRANB1

1

11

High-throughput

0.479

High

299005

LIMA1
LIM domain and actin-binding protein 1

1

20

High-throughput

0.479

High

157269

BCKD
Branched-chain alpha-ketoacid dehydrogenase kinase

1

1

High-throughput

0.470

High

299007

V9HW98
14-3-3 protein epsilon

1

9

High-throughput

0.470

High

298970

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

High-throughput

0.460

High

239660

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

6

High-throughput

0.445

High

298971

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

20

High-throughput

0.445

High

298997

ZBT18
Zinc finger and BTB domain-containing protein 18

1

11

High-throughput

0.445

High

298985

SYNE3
Nesprin-3

1

20

High-throughput

0.437

High

298994

SNX27
Sorting nexin-27

1

20

High-throughput

0.437

High

298995

CEP63
Centrosomal protein of 63 kDa

1

20

High-throughput

0.407

High

298989

ATPF2
ATP synthase mitochondrial F1 complex assembly factor 2

2

0

High-throughput

0.341

High


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Last updated: 15 Jul 2024