HitPredict

Interactor 1: CDK1 (P06493)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)
Gene: CDK1

Interactor 2: CCNE1 (P24864)
G1/S-specific cyclin-E1
Gene: CCNE1

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.915

The method score is based on:

Property Details
Experiments 36736316, 9891079, 1388288, 9053846, 1833068
Identification Methods affinity chromatography technology, biochemical, biophysical
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cyclin_C~Pkinase, Cyclin_N~Pkinase
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005813 - centrosome
and 4 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 297
Hs

1 410
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024