HitPredict

Interactor 1: CDK1 (P06493)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)
Gene: CDK1

Interactor 2: FLT3 (P36888)
Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)
Gene: FLT3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~Pkinase
Common GO terms	GO:0005524 - ATP binding GO:0031100 - animal organ regeneration
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 297 Hs			1 993
+	Hs
		414724 CDK1_HUMAN (1-297): 2.82e-143: 406: 100.00		VGFR1_HUMAN (74-537): 1.47e-36: 152: 14.31
+	Hs
		507863 CDK2_HUMAN (1-297): 3.26e-149: 421: 65.32		FGFR1_HUMAN (6-360): 2.83e-24: 111: 10.90
+	Hs
		414788 CDK1_HUMAN (1-297): 2.82e-143: 406: 100.00		VGFR3_HUMAN (70-533): 8.45e-27: 120: 14.15
+	Hs
		609180 CDK2_HUMAN (1-297): 3.26e-149: 421: 65.32		FGFR3_HUMAN (20-260): 5.2e-21: 101: 9.09
+	Hs
		414702 CDK1_HUMAN (1-297): 2.82e-143: 406: 100.00		FGFR1_HUMAN (6-360): 2.83e-24: 111: 10.90
+	Hs
		414738 CDK1_HUMAN (1-297): 2.82e-143: 406: 100.00		FGFR3_HUMAN (20-260): 5.2e-21: 101: 9.09
+	Hs
		414737 CDK1_HUMAN (1-297): 2.82e-143: 406: 100.00		FGFR4_HUMAN (47-355): 1.59e-17: 89.8: 11.67
+	Hs
		507952 CDK16_HUMAN (1-297): 6.03e-124: 364: 51.68		FGFR1_HUMAN (6-360): 2.83e-24: 111: 10.90