HitPredict

Interactor 1: CDK1 (P06493)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)
Gene: CDK1

Interactor 2: SPAG5 (Q96R06)
Sperm-associated antigen 5 (Astrin) (Deepest) (Mitotic spindle-associated protein p126) (MAP126)
Gene: SPAG5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	11549262
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030496 - midbody GO:0051301 - cell division GO:0072686 - mitotic spindle
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 297 Hs			1 1193
+	Hs
		528401 CDK2_HUMAN (1-297): 3.26e-149: 421: 65.32		MYH8_HUMAN (287-953): 3.4e-31: 135: 11.77
+	Hs
		528405 CDK3_HUMAN (1-289): 1.71e-144: 410: 66.78		MYH8_HUMAN (287-953): 3.4e-31: 135: 11.77
+	Hs
		522542 CDK3_HUMAN (1-289): 1.71e-144: 410: 66.78		MYH1_HUMAN (287-962): 1.25e-30: 133: 11.18
+	Hs
		502908 CDK3_HUMAN (1-289): 1.71e-144: 410: 66.78		MYH3_HUMAN (173-1134): 9.39e-30: 131: 11.22
+	Hs
		960128 CDK3_HUMAN (1-289): 1.71e-144: 410: 66.78		MYH2_HUMAN (192-1011): 9.96e-28: 124: 10.37
+	Hs
		960129 CDK3_HUMAN (1-289): 1.71e-144: 410: 66.78		MYH13_HUMAN (163-961): 2.75e-24: 113: 9.10
+	Hs
		551610 CDK2_HUMAN (1-297): 3.26e-149: 421: 65.32		DESP_HUMAN (501-1190): 6.44e-19: 95.8: 11.43
+	Hs
		522604 CDK3_HUMAN (1-289): 1.71e-144: 410: 66.78		MYH7_HUMAN (154-896): 6.03e-22: 105: 11.91
+	Hs
		625530 CDK2_HUMAN (1-297): 3.26e-149: 421: 65.32		MY18A_HUMAN (692-1192): 6.2e-16: 85.8: 13.78
+	Hs
		414713 CDK1_HUMAN (1-297): 2.82e-143: 406: 100.00		DESP_HUMAN (501-1190): 6.44e-19: 95.8: 11.43
+	Hs
		625446 CDK2_HUMAN (1-297): 3.26e-149: 421: 65.32		PLEC_HUMAN (462-1139): 9.56e-12: 72: 14.40
+	Hs
		625177 CDK2_HUMAN (1-297): 3.26e-149: 421: 65.32		MYH10_HUMAN (837-1188): 2.71e-11: 70.7: 11.33
+	Hs
		625176 CDK2_HUMAN (1-297): 3.26e-149: 421: 65.32		MYH9_HUMAN (873-1192): 7.59e-11: 69.1: 13.04
+	Hs
		528368 CDK3_HUMAN (1-289): 1.71e-144: 410: 66.78		MYH6_HUMAN (958-1190): 3.59e-09: 63.7: 14.16
+	Hs
		148286 CDK1_HUMAN (1-297): 2.82e-143: 406: 100.00		CTRO_HUMAN (356-721): 3.32e-10: 66.9: 9.51