Protein: RL17A
Large ribosomal subunit protein uL22A (60S ribosomal protein L17-A) (L20A) (YL17)

Gene: RL17A, RPL17A
Organism: Saccharomyces cerevisiae S288C
Interactions: 245
UniProt ID: P05740

Gene Ontology (top 5):
GO:0000448 - cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181 - cytoplasmic translation
GO:0003735 - structural constituent of ribosome
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

433184

RPF2
Ribosome biogenesis protein RPF2

6

1

Small-scale

0.939

High

433256

NOG2
Nucleolar GTP-binding protein 2

5

4

Small-scale

0.702

High

433114

RL31A
Large ribosomal subunit protein eL31A

4

3

High-throughput

0.676

High

433251

PESC
Pescadillo homolog

4

1

Small-scale

0.672

High

433192

ENP1
Essential nuclear protein 1

3

1

Small-scale

0.656

High

414963

RL39
Large ribosomal subunit protein eL39

1

1

High-throughput

0.618

High

433097

RL17A
Large ribosomal subunit protein uL22A

1

3

High-throughput

0.618

High

433132

RL4A
Large ribosomal subunit protein uL4A

1

5

High-throughput

0.618

High

433199

SSF1
Ribosome biogenesis protein SSF1

1

1

Small-scale

0.618

High

433236

RL17B
Large ribosomal subunit protein uL22B

1

3

High-throughput

0.618

High

433244

RL4B
Large ribosomal subunit protein uL4B

1

5

High-throughput

0.618

High

433111

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

2

1

High-throughput

0.611

High

433202

NMD3
60S ribosomal export protein NMD3

2

1

High-throughput

0.611

High

433255

BRE5
UBP3-associated protein BRE5

2

3

High-throughput

0.611

High

433274

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

2

3

High-throughput

0.611

High

409821

RL25
Large ribosomal subunit protein uL23

2

2

High-throughput

0.584

High

433098

RL26A
Large ribosomal subunit protein uL24A

2

5

High-throughput

0.584

High

433099

RL33A
Large ribosomal subunit protein eL33A

2

2

High-throughput

0.584

High

433122

RL2A
Large ribosomal subunit protein uL2A

2

3

High-throughput

0.584

High

433151

SIS1
Protein SIS1

2

1

High-throughput

0.584

High

433157

RL16A
Large ribosomal subunit protein uL13A

2

5

High-throughput

0.584

High

433167

ZUO1
Zuotin

2

3

High-throughput

0.584

High

433174

MRT4
Ribosome assembly factor MRT4

2

4

Small-scale

0.584

High

433206

STM1
Suppressor protein STM1

2

1

Small-scale

0.584

High

433213

NOC2
Nucleolar complex protein 2

2

1

Small-scale

0.584

High

433248

NSA1
Ribosome biogenesis protein NSA1

2

2

Small-scale

0.584

High

433249

LSG1
Large subunit GTPase 1

2

4

High-throughput

0.584

High

433276

RL6A
Large ribosomal subunit protein eL6A

2

2

High-throughput

0.584

High

433294

RQC1
Ribosome quality control complex subunit 1

2

1

Small-scale

0.584

High

433310

TMA46
Translation machinery-associated protein 46

2

1

High-throughput

0.584

High

433200

RPF1
Ribosome production factor 1

1

2

High-throughput

0.575

High

433197

CIC1
Proteasome-interacting protein CIC1

2

1

High-throughput

0.571

High

433258

JJJ1
J protein JJJ1

2

1

High-throughput

0.571

High

391972

HSP82
ATP-dependent molecular chaperone HSP82

2

0

High-throughput

0.559

High

433237

ALB1
Ribosome biogenesis protein ALB1

2

0

High-throughput

0.559

High

433154

PWP2
Periodic tryptophan protein 2

1

3

High-throughput

0.536

High

433163

XPO1
Exportin-1

1

2

High-throughput

0.536

High

433168

RPD3
Histone deacetylase RPD3

1

5

High-throughput

0.536

High

433323

RRP12
Ribosomal RNA-processing protein 12

1

1

High-throughput

0.536

High

433228

DSN1
Kinetochore-associated protein DSN1

2

1

High-throughput

0.533

High

433238

URB2
Nucleolar pre-ribosomal-associated protein 2

2

1

Small-scale

0.533

High

433266

ORC1
Origin recognition complex subunit 1

2

2

High-throughput

0.521

High

433311

NOP53
Ribosome biogenesis protein NOP53

2

2

Small-scale

0.521

High

433278

NOG1
Nucleolar GTP-binding protein 1

1

4

Small-scale

0.515

High

433216

ARB1
ABC transporter ATP-binding protein ARB1

1

0

High-throughput

0.513

High

433260

NAT10
RNA cytidine acetyltransferase

1

1

High-throughput

0.489

High

433129

SSBP1
Single-stranded nucleic acid-binding protein

1

0

High-throughput

0.480

High

149466

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

154102

RL36B
Large ribosomal subunit protein eL36B

1

3

High-throughput

0.479

High

383041

RLA4
Large ribosomal subunit protein P2B

1

3

High-throughput

0.479

High

409644

RL24A
Large ribosomal subunit protein eL24A

1

4

High-throughput

0.479

High

427054

RLA0
Large ribosomal subunit protein uL10

1

4

High-throughput

0.479

High

427509

RLA1
Large ribosomal subunit protein P1A

1

3

High-throughput

0.479

High

427631

RLA2
Large ribosomal subunit protein P2A

1

3

High-throughput

0.479

High

432431

RL7A
Large ribosomal subunit protein uL30A

1

6

High-throughput

0.479

High

432756

RL9A
Large ribosomal subunit protein uL6A

1

3

High-throughput

0.479

High

432941

RL6B
Large ribosomal subunit protein eL6B

1

2

High-throughput

0.479

High

433100

RL36A
Large ribosomal subunit protein eL36A

1

3

High-throughput

0.479

High

433101

RL29
Large ribosomal subunit protein eL29

1

1

High-throughput

0.479

High

433102

RL15A
Large ribosomal subunit protein eL15A

1

1

High-throughput

0.479

High

433103

RL22A
Large ribosomal subunit protein eL22A

1

2

High-throughput

0.479

High

433104

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

433105

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

433106

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

3

High-throughput

0.479

High

433108

SC160
Protein SCP160

1

1

High-throughput

0.479

High

433109

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

433110

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.479

High

433113

RL27B
Large ribosomal subunit protein eL27B

1

1

High-throughput

0.479

High

433115

RL31B
Large ribosomal subunit protein eL31B

1

3

High-throughput

0.479

High

433116

RL40A
Ubiquitin-ribosomal protein eL40A fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40A

1

3

High-throughput

0.479

High

433117

RL20B
Large ribosomal subunit protein eL20B

1

1

High-throughput

0.479

High

433118

RL43B
Large ribosomal subunit protein eL43B

1

1

High-throughput

0.479

High

433119

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

433120

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.479

High

433121

RL1A
Large ribosomal subunit protein uL1A

1

4

High-throughput

0.479

High

433123

RL18B
Large ribosomal subunit protein eL18B

1

1

High-throughput

0.479

High

433124

RL12B
Large ribosomal subunit protein uL11B

1

1

High-throughput

0.479

High

433126

RL19B
Large ribosomal subunit protein eL19

1

2

High-throughput

0.479

High

433127

RL35A
Large ribosomal subunit protein uL29A

1

2

High-throughput

0.479

High

433131

RLA3
Large ribosomal subunit protein P1B

1

3

High-throughput

0.479

High

433134

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.479

High

433138

RL30
Large ribosomal subunit protein eL30

1

2

High-throughput

0.479

High

433139

RL3
Large ribosomal subunit protein uL3

1

2

High-throughput

0.479

High

433141

RL8A
Large ribosomal subunit protein eL8A

1

3

High-throughput

0.479

High

433145

PWP1
Periodic tryptophan protein 1

1

5

High-throughput

0.479

High

433147

KCC2
Calcium/calmodulin-dependent protein kinase II

1

2

High-throughput

0.479

High

433148

RL24B
Large ribosomal subunit protein eL24B

1

4

High-throughput

0.479

High

433149

DBP2
ATP-dependent RNA helicase DBP2

1

1

High-throughput

0.479

High

433152

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.479

High

433156

RL5
Large ribosomal subunit protein uL18

1

2

High-throughput

0.479

High

433158

RL16B
Large ribosomal subunit protein uL13B

1

5

High-throughput

0.479

High

433161

HRR25
Casein kinase I homolog HRR25

1

2

Small-scale

0.479

High

433162

RL8B
Large ribosomal subunit protein eL8B

1

3

High-throughput

0.479

High

433164

HS104
Heat shock protein 104

1

1

High-throughput

0.479

High

433165

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

433170

AFG2
ATPase family gene 2 protein

1

5

Small-scale

0.479

High

433172

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.479

High

433175

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.479

High

433178

RRP1
Ribosomal RNA-processing protein 1

1

1

Small-scale

0.479

High

433182

RL14A
Large ribosomal subunit protein eL14A

1

4

High-throughput

0.479

High

433185

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

1

High-throughput

0.479

High

433187

GBLP
Small ribosomal subunit protein RACK1

1

5

High-throughput

0.479

High

433188

RL32
Large ribosomal subunit protein eL32

1

2

High-throughput

0.479

High

433190

GID4
GID complex substrate-recognition subunit 4

1

1

High-throughput

0.479

High

433195

ECM29
Proteasome component ECM29

1

1

High-throughput

0.479

High

433196

RL14B
Large ribosomal subunit protein eL14B

1

4

High-throughput

0.479

High

433198

SSZ1
Ribosome-associated complex subunit SSZ1

1

3

High-throughput

0.479

High

433208

DHH1
ATP-dependent RNA helicase DHH1

1

7

High-throughput

0.479

High

433209

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

433210

ECM1
Shuttling pre-60S factor ECM1

1

1

High-throughput

0.479

High

433211

RBG1
Ribosome-interacting GTPase 1

1

2

High-throughput

0.479

High

433212

IF2P
Eukaryotic translation initiation factor 5B

1

3

High-throughput

0.479

High

433220

RL13B
Large ribosomal subunit protein eL13B

1

4

High-throughput

0.479

High

433223

YIQ1
Uncharacterized protein YIL161W

1

1

High-throughput

0.479

High

433224

TM108
Protein TMA108

1

2

High-throughput

0.479

High

433226

RL34B
Large ribosomal subunit protein eL34B

1

4

High-throughput

0.479

High

433229

RLP7
Ribosome biogenesis protein RLP7

1

6

High-throughput

0.479

High

433230

RL10
Large ribosomal subunit protein uL16

1

3

High-throughput

0.479

High

433232

ELP2
Elongator complex protein 2

1

3

High-throughput

0.479

High

433242

RL37A
Large ribosomal subunit protein eL37A

1

3

High-throughput

0.479

High

433243

RL38
Large ribosomal subunit protein eL38

1

1

High-throughput

0.479

High

433245

RL9B
Large ribosomal subunit protein uL6B

1

3

High-throughput

0.479

High

433246

RL37B
Large ribosomal subunit protein eL37B

1

3

High-throughput

0.479

High

433250

RL26B
Large ribosomal subunit protein uL24B

1

5

High-throughput

0.479

High

433252

YG3A
Uncharacterized protein YGR130C

1

2

Small-scale

0.479

High

433257

GIS2
Zinc finger protein GIS2

1

5

High-throughput

0.479

High

433261

NOP15
Ribosome biogenesis protein 15

1

2

High-throughput

0.479

High

433262

NST1
Stress response protein NST1

1

1

High-throughput

0.479

High

433265

FAP1
FKBP12-associated protein 1

1

2

High-throughput

0.479

High

433269

RL22B
Large ribosomal subunit protein eL22B

1

2

High-throughput

0.479

High

433270

RL34A
Large ribosomal subunit protein eL34A

1

4

High-throughput

0.479

High

433272

SEN1
Helicase SEN1

1

1

High-throughput

0.479

High

433275

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

433277

RL21A
Large ribosomal subunit protein eL21A

1

3

High-throughput

0.479

High

433280

TOM1
E3 ubiquitin-protein ligase TOM1

1

4

High-throughput

0.479

High

433282

HAS1
ATP-dependent RNA helicase HAS1

1

10

High-throughput

0.479

High

433283

ARX1
Probable metalloprotease ARX1

1

2

High-throughput

0.479

High

433285

HMO1
High mobility group protein 1

1

2

High-throughput

0.479

High

433290

LTN1
E3 ubiquitin-protein ligase listerin

1

1

Small-scale

0.479

High

433300

NOC4
Nucleolar complex protein 4

1

4

High-throughput

0.479

High

433302

ELP1
Elongator complex protein 1

1

1

High-throughput

0.479

High

433306

RIX7
Ribosome biogenesis ATPase RIX7

1

5

High-throughput

0.479

High

433309

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.479

High

433313

CHS5
Chitin biosynthesis protein CHS5

1

2

High-throughput

0.479

High

433316

RL7B
Large ribosomal subunit protein uL30B

1

6

High-throughput

0.479

High

433318

DBP10
ATP-dependent RNA helicase DBP10

1

9

High-throughput

0.479

High

433320

RQC2
Ribosome quality control complex subunit 2

1

1

High-throughput

0.479

High

433321

RL21B
Large ribosomal subunit protein eL21B

1

3

High-throughput

0.479

High

433322

RL13A
Large ribosomal subunit protein eL13A

1

4

High-throughput

0.479

High

433324

RL11B
Large ribosomal subunit protein uL5B

1

2

High-throughput

0.479

High

383230

RL28
Large ribosomal subunit protein uL15

1

0

High-throughput

0.458

High

383397

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.458

High

433112

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.458

High

433125

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

433128

RS32B
Small ribosomal subunit protein eS32B

1

0

High-throughput

0.458

High

433133

PDR1
Transcription factor PDR1

1

0

High-throughput

0.458

High

433159

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

433166

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

0

High-throughput

0.458

High

433173

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

433179

ASK1
DASH complex subunit ASK1

1

0

Small-scale

0.458

High

433180

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

433183

LAS1
Protein LAS1

1

0

Small-scale

0.458

High

433194

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

433204

RIX1
Pre-rRNA-processing protein RIX1

1

0

Small-scale

0.458

High

433241

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

433247

DXO
Decapping nuclease RAI1

1

0

Small-scale

0.458

High

433279

ELP3
Elongator complex protein 3

1

0

High-throughput

0.458

High

433287

SEG1
Eisosome protein SEG1

1

0

Small-scale

0.458

High

433292

EIS1
Eisosome protein 1

1

0

Small-scale

0.458

High

433295

POC1
Proteasome chaperone 1

1

0

High-throughput

0.458

High

433299

RRP15
Ribosomal RNA-processing protein 15

1

0

Small-scale

0.458

High

433303

PBP4
Protein PBP4

1

0

High-throughput

0.458

High

433307

SGO1
Shugoshin

1

0

High-throughput

0.458

High

433130

HSP71
Heat shock protein SSA1

1

4

High-throughput

0.445

High

433143

ARF2
ADP-ribosylation factor 2

1

1

High-throughput

0.445

High

433155

SPB4
ATP-dependent rRNA helicase SPB4

1

7

High-throughput

0.445

High

433176

PIN4
RNA-binding protein PIN4

1

1

High-throughput

0.445

High

433191

YBP1
YAP1-binding protein 1

1

1

High-throughput

0.445

High

433203

NACA
Nascent polypeptide-associated complex subunit alpha

1

1

Small-scale

0.445

High

433219

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

433281

GCN5
Histone acetyltransferase GCN5

1

2

High-throughput

0.445

High

433136

ACOX
Acyl-coenzyme A oxidase

1

1

High-throughput

0.437

High

433140

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.437

High

433153

KRR1
KRR1 small subunit processome component

1

2

High-throughput

0.437

High

433160

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

433169

CHD1
Chromo domain-containing protein 1

1

4

High-throughput

0.437

High

433214

IF4F2
Eukaryotic initiation factor 4F subunit p130

1

1

High-throughput

0.437

High

433225

FIS1
Mitochondrial fission 1 protein

1

1

Small-scale

0.437

High

433233

UTP10
U3 small nucleolar RNA-associated protein 10

1

1

High-throughput

0.437

High

433234

SET4
SET domain-containing protein 4

1

1

Small-scale

0.437

High

433239

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.437

High

433253

SDA1
Protein SDA1

1

1

High-throughput

0.437

High

433254

H1
Histone H1

1

1

High-throughput

0.437

High

433259

IPI3
Pre-rRNA-processing protein IPI3

1

3

High-throughput

0.437

High

433264

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.437

High

433284

RUVB1
RuvB-like protein 1

1

2

High-throughput

0.437

High

433286

DHR1
Probable ATP-dependent RNA helicase DHR1

1

5

High-throughput

0.437

High

433288

UTP14
U3 small nucleolar RNA-associated protein 14

1

1

High-throughput

0.437

High

433291

RRP5
rRNA biogenesis protein RRP5

1

2

Small-scale

0.437

High

433296

YL278
Uncharacterized transcriptional regulatory protein YLR278C

1

1

High-throughput

0.437

High

433315

YRA1
RNA annealing protein YRA1

1

1

High-throughput

0.437

High

433319

RUVB2
RuvB-like protein 2

1

2

High-throughput

0.437

High

433107

NOT3
General negative regulator of transcription subunit 3

1

0

High-throughput

0.426

High

433193

REI1
Cytoplasmic 60S subunit biogenesis factor REI1

1

0

Small-scale

0.426

High

433205

BFR1
Nuclear segregation protein BFR1

1

0

High-throughput

0.426

High

433207

PCF11
Protein PCF11

1

0

High-throughput

0.426

High

433231

REF2
RNA end formation protein 2

1

0

High-throughput

0.426

High

433268

RUXF
Small nuclear ribonucleoprotein F

1

0

High-throughput

0.426

High

433273

NAM8
Protein NAM8

1

0

High-throughput

0.426

High

433135

TBP
TATA-box-binding protein

1

1

High-throughput

0.407

High

433144

ODO1
2-oxoglutarate dehydrogenase, mitochondrial

1

1

High-throughput

0.407

High

433146

REB1
DNA-binding protein REB1

1

2

High-throughput

0.407

High

433186

CCL1
Cyclin CCL1

1

1

High-throughput

0.407

High

433189

AP2A
AP-2 complex subunit alpha

1

1

High-throughput

0.407

High

433222

RFC2
Replication factor C subunit 2

1

1

High-throughput

0.407

High

433301

CFT1
Protein CFT1

1

1

High-throughput

0.407

High

433312

FAL1
ATP-dependent RNA helicase FAL1

1

5

High-throughput

0.407

High

433267

ERG13
Hydroxymethylglutaryl-CoA synthase

1

0

High-throughput

0.279

Low

433304

RXT3
Transcriptional regulatory protein RXT3

1

0

High-throughput

0.279

Low

433142

DAP2
Dipeptidyl aminopeptidase B

1

0

Small-scale

0.249

Low

433177

URB1
Nucleolar pre-ribosomal-associated protein 1

1

0

High-throughput

0.249

Low

433181

EAP1
Protein EAP1

1

0

High-throughput

0.249

Low

433201

WSS1
DNA-dependent metalloprotease WSS1

1

0

Small-scale

0.249

Low

433218

THO1
Protein THO1

1

0

High-throughput

0.249

Low

433227

SNL1
HSP70 co-chaperone SNL1

1

0

Small-scale

0.249

Low

433271

NUM1
Nuclear migration protein NUM1

1

0

High-throughput

0.249

Low

433289

VBA4
Vacuolar basic amino acid transporter 4

1

0

High-throughput

0.249

Low

433298

ESF1
Pre-rRNA-processing protein ESF1

1

0

High-throughput

0.249

Low

433314

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.249

Low

433137

RSR1
Ras-related protein RSR1

1

0

High-throughput

0.232

Low

433150

MED19
Mediator of RNA polymerase II transcription subunit 19

1

0

High-throughput

0.232

Low

433171

PMP1
Plasma membrane ATPase proteolipid 1

1

0

High-throughput

0.232

Low

433215

OXA1
Mitochondrial inner membrane protein OXA1

1

0

High-throughput

0.232

Low

433217

PIC2
Mitochondrial phosphate carrier protein 2

1

0

High-throughput

0.232

Low

433221

ELO3
Fatty acid elongase 3

1

0

High-throughput

0.232

Low

433235

PHO86
Inorganic phosphate transporter PHO86

1

0

High-throughput

0.232

Low

433240

SEC16
COPII coat assembly protein SEC16

1

0

High-throughput

0.232

Low

433263

SFB2
SED5-binding protein 2

1

0

High-throughput

0.232

Low

433293

ERP1
Protein ERP1

1

0

High-throughput

0.232

Low

433297

YP114
Uncharacterized TLC domain-containing protein YPR114W

1

0

High-throughput

0.232

Low

433305

CRLS1
Cardiolipin synthase

1

0

High-throughput

0.232

Low

433308

SYC1
Protein SYC1

1

0

High-throughput

0.232

Low

433317

MAM3
Protein MAM3

1

0

High-throughput

0.232

Low

433325

TECR
Very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025