Interactor 1: SIR2 (P06700)
NAD-dependent histone deacetylase SIR2 (EC 2.3.1.286) (Regulatory protein SIR2) (Silent information regulator 2)
Gene: SIR2

Interactor 2: MCM10 (P32354)
Minichromosome maintenance protein 10 (Protein DNA43)
Gene: MCM10

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 0.55 0.636

The method score is based on:

Property Details
Experiments 16328881, 19064704, 16085704
Identification Methods two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
GO:0030466 - silent mating-type cassette heterochromatin formation
GO:0031509 - subtelomeric heterochromatin formation
GO:0046872 - metal ion binding
Homologous interactions 0

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Last updated: 15 Jul 2024