Interactor 1: SIR3 (P06701)
Regulatory protein SIR3 (Silent information regulator 3)
Gene: SIR3

Interactor 2: SIR4 (P11978)
Regulatory protein SIR4 (Silent information regulator 4)
Gene: SIR4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.55 0.734

The method score is based on:

Property Details
Experiments 8779721, 11805837, 8752220, 9122169, 11689698, 7958893, 10835378, 15907466, 15899856, 25453095, 16717101, 30455303, 18794362, 12791253, 15282295, 16554755, 34817085, 19217406, 21822217, 21896656 and 2 others

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Identification Methods coimmunoprecipitation, experimental interaction detection, anti tag coimmunoprecipitation, affinity chromatography technology, two hybrid, pull down, far western blotting, biochemical, tandem affinity purification, classical fluorescence spectroscopy and 1 others

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Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000781 - chromosome, telomeric region
GO:0003690 - double-stranded DNA binding
GO:0005677 - chromatin silencing complex
GO:0006303 - double-strand break repair via nonhomologous end joining
GO:0030466 - silent mating-type cassette heterochromatin formation
and 5 others

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Homologous interactions 0

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Last updated: 15 Jul 2024