HitPredict

Interactor 1: S10A9 (P06702)
Protein S100-A9 (Calgranulin-B) (Calprotectin L1H subunit) (Leukocyte L1 complex heavy chain) (Migration inhibitory factor-related protein 14) (MRP-14) (p14) (S100 calcium-binding protein A9)
Gene: S100A9

Interactor 2: CUL2 (Q13617)
Cullin-2 (CUL-2)
Gene: CUL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	24981860, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 114 Hs			1 745
+	Hs
		1041388 HORN_HUMAN (5-97): 3.47e-32: 120: 29.03		CUL2_HUMAN (1-745): 0: 840: 100.00
+	Hs
		638955 S100P_HUMAN (5-97): 2.82e-35: 118: 36.56		CUL2_HUMAN (1-745): 0: 840: 100.00
+	Hs
		1041353 FILA2_HUMAN (5-106): 5.21e-28: 108: 30.91		CUL2_HUMAN (1-745): 0: 840: 100.00
+	Hs
		396732 S10A8_HUMAN (5-100): 3.01e-29: 102: 25.00		CUL2_HUMAN (1-745): 0: 840: 100.00
+	Hs
		596272 FILA_HUMAN (5-107): 2e-23: 95.4: 34.62		CUL2_HUMAN (1-745): 0: 840: 100.00
+	Hs
		1043087 HORN_HUMAN (5-97): 3.47e-32: 120: 29.03		CUL4A_HUMAN (4-745): 0: 773: 26.86
+	Hs
		1043033 FILA2_HUMAN (5-106): 5.21e-28: 108: 30.91		CUL4A_HUMAN (4-745): 0: 773: 26.86
+	Hs
		678447 S10A7_HUMAN (6-105): 8.64e-26: 94.2: 24.75		CUL4B_HUMAN (4-745): 0: 771: 27.79
+	Hs
		416487 S10A9_HUMAN (1-114): 4.07e-47: 148: 100.00		CUL5_HUMAN (7-745): 0: 627: 26.69
+	Hs
		678485 S10A7_HUMAN (6-105): 8.64e-26: 94.2: 24.75		CUL5_HUMAN (7-745): 0: 627: 26.69