HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: H12 (P16403)
Histone H1.2 (Histone H1c) (Histone H1d) (Histone H1s-1)
Gene: H1-2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	34349018, 26496610, 20431927
Identification Methods	cross-linking study, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0006334 - nucleosome assembly
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 213
+	Hs
		417905 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		H13_HUMAN (1-181): 4.78e-25: 99.5: 82.42
+	Hs
		417877 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		H14_HUMAN (1-172): 4.96e-18: 80.6: 88.37
+	Hs
		417904 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		H15_HUMAN (1-157): 2.05e-15: 74.1: 76.25
+	Hs
		418187 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		H11_HUMAN (38-182): 2.87e-15: 73.3: 62.07
+	Hs
		271259 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		H1T_HUMAN (1-183): 5.25e-24: 96.4: 53.40