HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: IKZF1 (Q13422)
DNA-binding protein Ikaros (Ikaros family zinc finger protein 1) (Lymphoid transcription factor LyF-1)
Gene: IKZF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35583604
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0032991 - protein-containing complex
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 519
+	Hs
		418468 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		ZFP62_HUMAN (30-518): 1.6e-165: 493: 14.84
+	Hs
		64134 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		ZN729_HUMAN (58-518): 6.11e-148: 457: 15.43
+	Hs
		418775 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		IKZF3_HUMAN (11-515): 4.42e-139: 413: 53.82
+	Hs
		271365 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		ZFP62_HUMAN (30-518): 1.6e-165: 493: 14.84
+	Hs
		64131 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		ZN729_HUMAN (58-518): 6.11e-148: 457: 15.43
+	Hs
		417909 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		ZNF16_HUMAN (1-114): 1.26e-33: 137: 7.90
+	Hs
		418665 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		IKZF5_HUMAN (62-193): 1.16e-11: 68.6: 33.33
+	Hs
		271444 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		ZN624_HUMAN (287-518): 3.13e-70: 242: 12.00
+	Hs
		271392 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		ZN184_HUMAN (386-519): 1.58e-43: 166: 15.67
+	Hs
		271254 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		ZNF16_HUMAN (1-114): 1.26e-33: 137: 7.90