Protein: PCAT1
Lysophosphatidylcholine acyltransferase 1 (LPC acyltransferase 1) (LPCAT-1) (LysoPC acyltransferase 1) (EC 2.3.1.23) (1-acylglycerol-3-phosphate O-acyltransferase) (EC 2.3.1.51) (1-acylglycerophosphocholine O-acyltransferase) (1-alkenylglycerophosphocholine O-acyltransferase) (EC 2.3.1.25) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acetyl-CoA:lyso-platelet-activating factor acetyltransferase) (Acetyl-CoA:lyso-PAF acetyltransferase) (Lyso-PAF acetyltransferase) (LysoPAFAT) (Acyltransferase-like 2) (Phosphonoformate immuno-associated protein 3)

Gene: PCAT1, LPCAT1
Organism: Homo sapiens
Interactions: 124
UniProt ID: Q8NF37

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0003841 - 1-acylglycerol-3-phosphate O-acyltransferase activity
GO:0005509 - calcium ion binding
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

171519

S27A2
Long-chain fatty acid transport protein 2

3

1

High-throughput

0.667

High

1130707

DIP2A
Disco-interacting protein 2 homolog A

3

0

High-throughput

0.638

High

1338477

MSTO1
Protein misato homolog 1

3

1

High-throughput

0.609

High

1104445

ILK
Scaffold protein ILK

2

0

High-throughput

0.602

High

412281

NTRK1
High affinity nerve growth factor receptor

2

9

High-throughput

0.594

High

1035793

KIF23
Kinesin-like protein KIF23

1

2

High-throughput

0.553

High

182676

GP182
G-protein coupled receptor 182

1

10

High-throughput

0.536

High

260916

RAMP3
Receptor activity-modifying protein 3

1

6

High-throughput

0.536

High

349493

TSN15
Tetraspanin-15

1

10

High-throughput

0.536

High

564089

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.536

High

846768

GRK6
G protein-coupled receptor kinase 6

1

2

High-throughput

0.536

High

939947

TPTE
Putative tyrosine-protein phosphatase TPTE

1

2

High-throughput

0.536

High

1098923

KLRD1
Natural killer cells antigen CD94

1

5

High-throughput

0.536

High

1235301

STYK1
Tyrosine-protein kinase STYK1

1

3

High-throughput

0.536

High

1243023

PKN3
Serine/threonine-protein kinase N3

1

1

High-throughput

0.536

High

1279527

ADCK2
Uncharacterized aarF domain-containing protein kinase 2

1

1

High-throughput

0.536

High

1316612

CDK20
Cyclin-dependent kinase 20

1

5

High-throughput

0.536

High

1325870

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

3

High-throughput

0.536

High

1338484

SG196
Protein O-mannose kinase

1

2

High-throughput

0.536

High

593685

BGAL
Beta-galactosidase

1

0

High-throughput

0.513

High

1338495

FBW1A
F-box/WD repeat-containing protein 1A

1

2

Small-scale

0.512

High

185867

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

1

High-throughput

0.501

High

891681

GSK3B
Glycogen synthase kinase-3 beta

1

7

Small-scale

0.501

High

710865

EPHB2
Ephrin type-B receptor 2

1

3

High-throughput

0.500

High

162014

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

1

3

High-throughput

0.489

High

724696

MK04
Mitogen-activated protein kinase 4

1

14

High-throughput

0.489

High

1112253

PEX6
Peroxisomal ATPase PEX6

1

1

High-throughput

0.489

High

1310243

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.489

High

1334436

ACBD4
Acyl-CoA-binding domain-containing protein 4

1

1

High-throughput

0.489

High

1337123

HIPK4
Homeodomain-interacting protein kinase 4

1

11

High-throughput

0.489

High

1338465

COQ8A
Atypical kinase COQ8A, mitochondrial

1

1

High-throughput

0.489

High

1338467

NEK7
Serine/threonine-protein kinase Nek7

1

4

High-throughput

0.489

High

1338474

PSKH2
Serine/threonine-protein kinase H2

1

8

High-throughput

0.489

High

1338488

NRBP2
Nuclear receptor-binding protein 2

1

3

High-throughput

0.489

High

1338497

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

3

High-throughput

0.489

High

1338499

RPKL1
Ribosomal protein S6 kinase-like 1

1

3

High-throughput

0.489

High

126706

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

174001

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

8

High-throughput

0.479

High

242332

PRKN
E3 ubiquitin-protein ligase parkin

1

6

High-throughput

0.479

High

375743

RASK
GTPase KRas

1

5

High-throughput

0.479

High

404238

GCR
Glucocorticoid receptor

1

6

High-throughput

0.479

High

417603

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

3

High-throughput

0.479

High

418283

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

3

High-throughput

0.479

High

466365

RHOC
Rho-related GTP-binding protein RhoC

1

16

High-throughput

0.479

High

650308

FGFR3
Fibroblast growth factor receptor 3

1

6

High-throughput

0.479

High

675087

TNR6
Tumor necrosis factor receptor superfamily member 6

1

2

High-throughput

0.479

High

847609

SSRA
Translocon-associated protein subunit alpha

1

2

High-throughput

0.479

High

904015

BAP31
B-cell receptor-associated protein 31

1

3

High-throughput

0.479

High

955388

CDC42
Cell division control protein 42 homolog

1

17

High-throughput

0.479

High

962284

RHOA
Transforming protein RhoA

1

18

High-throughput

0.479

High

978171

RHOB
Rho-related GTP-binding protein RhoB

1

18

High-throughput

0.479

High

988537

RAC1
Ras-related C3 botulinum toxin substrate 1

1

16

High-throughput

0.479

High

1015612

RHOG
Rho-related GTP-binding protein RhoG

1

15

High-throughput

0.479

High

1027094

REEP5
Receptor expression-enhancing protein 5

1

3

High-throughput

0.479

High

1031823

LAT1
Large neutral amino acids transporter small subunit 1

1

8

High-throughput

0.479

High

1113744

CUL3
Cullin-3

1

1

High-throughput

0.479

High

1249034

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

1252899

BAKOR
Beclin 1-associated autophagy-related key regulator

1

1

High-throughput

0.479

High

1270907

RHOU
Rho-related GTP-binding protein RhoU

1

17

High-throughput

0.479

High

1289817

PAQR2
Adiponectin receptor protein 2

1

3

Small-scale

0.479

High

1294213

GOLI
E3 ubiquitin-protein ligase RNF130

1

4

High-throughput

0.479

High

1322899

CXD3
Gap junction delta-3 protein

1

2

High-throughput

0.479

High

1333905

DHB11
Estradiol 17-beta-dehydrogenase 11

1

4

High-throughput

0.479

High

1334468

RN149
E3 ubiquitin-protein ligase RNF149

1

4

High-throughput

0.479

High

1334665

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

1338475

SEC62
Translocation protein SEC62

1

3

High-throughput

0.479

High

1338478

DERL1
Derlin-1

1

2

High-throughput

0.479

High

1338482

RHOJ
Rho-related GTP-binding protein RhoJ

1

17

High-throughput

0.479

High

1338483

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.479

High

1338487

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

1338490

TM216
Transmembrane protein 216

1

3

High-throughput

0.479

High

1338492

TES
Testin

1

1

High-throughput

0.479

High

1338494

AMFR
E3 ubiquitin-protein ligase AMFR

1

1

High-throughput

0.479

High

1338498

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

1

Small-scale

0.479

High

831092

CCNF
Cyclin-F

1

3

High-throughput

0.470

High

537544

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

580661

AMPN
Aminopeptidase N

1

0

High-throughput

0.458

High

767269

MERL
Merlin

1

0

High-throughput

0.458

High

772398

PCKGC
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]

1

0

Small-scale

0.458

High

927070

ATX3
Ataxin-3

1

0

Small-scale

0.458

High

941940

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.458

High

1041183

CAV1
Caveolin-1

1

0

High-throughput

0.458

High

1338479

BBS2
BBSome complex member BBS2

1

0

High-throughput

0.458

High

1338491

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

0

High-throughput

0.458

High

396549

ESR1
Estrogen receptor

1

6

High-throughput

0.445

High

530099

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.445

High

538786

GTR2
Solute carrier family 2, facilitated glucose transporter member 2

1

9

High-throughput

0.445

High

844948

EAA2
Excitatory amino acid transporter 2

1

1

High-throughput

0.445

High

943997

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

3

High-throughput

0.445

High

1209410

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

8

High-throughput

0.445

High

1335632

MOT11
Monocarboxylate transporter 11

1

5

High-throughput

0.445

High

1338466

S7A14
Solute carrier family 7 member 14

1

8

High-throughput

0.445

High

294050

CD123
Translation initiation factor eIF2 assembly protein

1

5

High-throughput

0.437

High

342261

BRD1
Bromodomain-containing protein 1

1

4

High-throughput

0.437

High

521393

ARAF
Serine/threonine-protein kinase A-Raf

1

1

Small-scale

0.437

High

589200

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

695983

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

768682

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

883286

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

1

High-throughput

0.437

High

970802

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.437

High

1004855

RNF4
E3 ubiquitin-protein ligase RNF4

1

3

High-throughput

0.437

High

1252442

M3K15
Mitogen-activated protein kinase kinase kinase 15

1

8

High-throughput

0.437

High

1254715

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.437

High

1338470

ESR2
Estrogen receptor beta

1

6

High-throughput

0.437

High

1338471

FBXW7
F-box/WD repeat-containing protein 7

1

2

High-throughput

0.437

High

1338472

OTUL
Ubiquitin thioesterase otulin

1

5

Small-scale

0.437

High

1338473

DOCK7
Dedicator of cytokinesis protein 7

1

1

High-throughput

0.437

High

1338481

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

3

High-throughput

0.437

High

1338486

ECT2
Protein ECT2

1

4

High-throughput

0.437

High

1338489

OTULL
Inactive ubiquitin thioesterase OTULINL

1

5

High-throughput

0.437

High

1338493

XPO7
Exportin-7

1

3

High-throughput

0.437

High

1338496

AAR2
Protein AAR2 homolog

1

1

High-throughput

0.437

High

1309388

SPNS2
Sphingosine-1-phosphate transporter SPNS2

1

0

High-throughput

0.426

High

1272068

SYPM
Probable proline--tRNA ligase, mitochondrial

1

0

High-throughput

0.279

Low

1338476

METH
Methionine synthase

1

0

High-throughput

0.279

Low

156053

SOCS6
Suppressor of cytokine signaling 6

1

0

High-throughput

0.269

Low

1129657

MDC1
Mediator of DNA damage checkpoint protein 1

1

0

High-throughput

0.249

Low

1162432

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low

1229570

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

1338468

SAP25
Histone deacetylase complex subunit SAP25

1

0

Small-scale

0.249

Low

1338469

NUDC2
NudC domain-containing protein 2

1

0

High-throughput

0.249

Low

1338480

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.249

Low

1338485

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.249

Low

1238059

S18B1
MFS-type transporter SLC18B1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025