HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: LARP4 (Q71RC2)
La-related protein 4 (La ribonucleoprotein domain family member 4)
Gene: LARP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.671

Property	Details
Experiments	26496610, 30021884, 35271311
Identification Methods	affinity chromatography technology, proximity labelling technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol GO:0016020 - membrane GO:0045727 - positive regulation of translation
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 724
+	Hs
		418509 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		LAR4B_HUMAN (9-724): 5.72e-59: 214: 32.70
+	Hs
		418333 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		LARP7_HUMAN (123-365): 8.03e-34: 139: 17.22
+	Hs
		418378 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		LARP1_HUMAN (98-620): 1.39e-30: 131: 14.72
+	Hs
		418503 NPM_HUMAN (1-294): 1.47e-143: 407: 100.00		TITIN_HUMAN (369-718): 1.64e-09: 64: 10.26
+	Hs
		271333 NPM3_HUMAN (10-119): 6.13e-58: 185: 43.75		LARP7_HUMAN (123-365): 8.03e-34: 139: 17.22