Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: NPM2 (Q86SE8)
Nucleoplasmin-2
Gene: NPM2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.972

The method score is based on:

Property Details
Experiments 25416956, 26871637, 28514442, 32296183, 33961781, unassigned1304, 31515488
Identification Methods two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, bimolecular fluorescence complementation, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Nucleoplasmin~Nucleoplasmin
Common GO terms GO:0003682 - chromatin binding
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
and 3 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 294
Hs

1 214
+ Hs
+ Hs
+ Mm
+ Xl
+ Hs
+ Xl

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Last updated: 15 Jul 2024