HitPredict

Interactor 1: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Interactor 2: RHOG (P84095)
Rho-related GTP-binding protein RhoG
Gene: RHOG

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	33513601
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0007015 - actin filament organization GO:0070062 - extracellular exosome
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 285 Hs			1 191
+	Hs
		451225 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73
+	Hs
		925177 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88
+	Hs
		931991 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		RHOG_HUMAN (1-191): 9.12e-82: 242: 100.00
+	Hs
		925356 MRCKG_HUMAN (3-285): 1.48e-14: 75.7: 10.65		RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88
+	Hs
		925766 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88
+	Hs
		894128 MRCKG_HUMAN (3-285): 1.48e-14: 75.7: 10.65		CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73
+	Hs
		951494 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		RHOG_HUMAN (1-191): 9.12e-82: 242: 100.00
+	Hs
		545725 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		RAC2_HUMAN (1-191): 1.28e-78: 234: 71.35
+	Hs
		894628 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73
+	Hs
		901094 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62
+	Hs
		564571 MRCKG_HUMAN (3-285): 1.48e-14: 75.7: 10.65		RHOQ_HUMAN (4-189): 5.74e-73: 220: 56.84
+	Hs
		892702 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		RAC3_HUMAN (1-177): 1.67e-75: 226: 72.88
+	Hs
		564758 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		RHOQ_HUMAN (4-189): 5.74e-73: 220: 56.84