HitPredict

Interactor 1: RHO1 (P06780)
GTP-binding protein RHO1 (EC 3.6.5.2) (Rho-type GTPase 1)
Gene: RHO1

Interactor 2: KOG1 (P38873)
Target of rapamycin complex 1 subunit KOG1 (TORC1 subunit KOG1) (Kontroller of growth protein 1) (Local anesthetic-sensitive protein 24) (Regulatory-associated protein of TOR) (Raptor)
Gene: KOG1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	26212438, 22445487
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000329 - fungal-type vacuole membrane GO:0005739 - mitochondrion GO:0005886 - plasma membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 209 Sc			1 1557
+	Hs
		564607 RHOQ_HUMAN (1-208): 6.16e-83: 246: 45.67		RPTOR_HUMAN (20-1552): 0: 1188: 28.59
+	Hs
		918902 RAB1A_HUMAN (1-207): 9.93e-72: 218: 23.39		RPTOR_HUMAN (20-1552): 0: 1188: 28.59
+	Hs
		436191 RHOC_HUMAN (8-209): 5.39e-95: 276: 66.34		LIS1_HUMAN (1348-1552): 7.62e-38: 149: 9.80
+	Hs
		436516 RHOC_HUMAN (8-209): 5.39e-95: 276: 66.34		GBB4_HUMAN (1274-1553): 6.2e-34: 136: 12.37
+	Hs
		915985 RHOB_HUMAN (8-187): 4.55e-92: 269: 68.89		GBB4_HUMAN (1274-1553): 6.2e-34: 136: 12.37
+	Mm
		892718 CDC42_MOUSE (10-209): 1.64e-82: 245: 48.50		LIS1_MOUSE (1348-1552): 7.27e-38: 149: 9.80
+	Hs
		925630 RAC1_HUMAN (11-209): 1.93e-76: 229: 53.77		GBB4_HUMAN (1274-1553): 6.2e-34: 136: 12.37
+	Hs
		436239 RHOC_HUMAN (8-209): 5.39e-95: 276: 66.34		WDR5_HUMAN (1043-1284): 1.48e-16: 85: 9.31
+	Hs
		545626 RAC2_HUMAN (11-209): 6.55e-73: 220: 51.76		GBB4_HUMAN (1274-1553): 6.2e-34: 136: 12.37
+	Hs
		900924 RHOA_HUMAN (12-209): 4.93e-73: 220: 68.69		GBB4_HUMAN (1274-1553): 6.2e-34: 136: 12.37
+	Hs
		951353 RHOG_HUMAN (10-209): 6.09e-72: 218: 54.00		GBB4_HUMAN (1274-1553): 6.2e-34: 136: 12.37
+	Hs
		892604 RAC3_HUMAN (11-185): 1.19e-71: 217: 57.14		GBB4_HUMAN (1274-1553): 6.2e-34: 136: 12.37
+	Hs
		894451 CDC42_HUMAN (10-209): 1.74e-71: 217: 48.50		GBB4_HUMAN (1274-1553): 6.2e-34: 136: 12.37
+	Hs
		863392 CDC42_HUMAN (10-209): 1.74e-71: 217: 48.50		COPA_HUMAN (1199-1484): 2.15e-25: 117: 12.18
+	Hs
		900348 RHOA_HUMAN (12-209): 4.93e-73: 220: 68.69		WDR5_HUMAN (1043-1284): 1.48e-16: 85: 9.31
+	Hs
		903100 RAB1A_HUMAN (1-207): 9.93e-72: 218: 23.39		WDR5_HUMAN (1043-1284): 1.48e-16: 85: 9.31