Protein: RPC8
DNA-directed RNA polymerase III subunit RPC8 (RNA polymerase III subunit C8) (DNA-directed RNA polymerase III 25 kDa polypeptide) (RNA polymerase III subunit C25)

Gene: RPC8, RPC25
Organism: Saccharomyces cerevisiae S288C
Interactions: 39
UniProt ID: P35718

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003899 - DNA-directed RNA polymerase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005666 - RNA polymerase III complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

647078

RPC2
DNA-directed RNA polymerase III subunit RPC2

7

11

Small-scale

0.960

High

402210

RPC1
DNA-directed RNA polymerase III subunit RPC1

5

12

High-throughput

0.930

High

632250

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

4

5

High-throughput

0.896

High

776305

RPC9
DNA-directed RNA polymerase III subunit RPC9

6

0

Small-scale

0.888

High

459066

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

6

8

Small-scale

0.732

High

674404

RPC4
DNA-directed RNA polymerase III subunit RPC4

7

0

Small-scale

0.714

High

734928

RPC3
DNA-directed RNA polymerase III subunit RPC3

5

1

High-throughput

0.714

High

776295

RPC5
DNA-directed RNA polymerase III subunit RPC5

5

2

High-throughput

0.714

High

632157

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

5

4

Small-scale

0.713

High

748123

RPC6
DNA-directed RNA polymerase III subunit RPC6

4

1

High-throughput

0.694

High

645046

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

3

4

High-throughput

0.662

High

699993

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

3

5

High-throughput

0.657

High

609186

RPC7
DNA-directed RNA polymerase III subunit RPC7

3

0

High-throughput

0.629

High

632334

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

2

5

High-throughput

0.621

High

708711

TF3B
Transcription factor IIIB 70 kDa subunit

2

4

High-throughput

0.584

High

776303

BUD27
Bud site selection protein 27

2

0

Small-scale

0.559

High

776297

RSP5
E3 ubiquitin-protein ligase RSP5

1

3

Small-scale

0.501

High

776311

RMD5
E3 ubiquitin-protein ligase RMD5

1

0

High-throughput

0.486

High

776301

ULP2
Ubiquitin-like-specific protease 2

1

1

High-throughput

0.481

High

776307

ULP1
Ubiquitin-like-specific protease 1

1

1

High-throughput

0.481

High

419401

H2A1
Histone H2A.1

1

1

High-throughput

0.479

High

419692

H2A2
Histone H2A.2

1

1

High-throughput

0.479

High

561462

TBP
TATA-box-binding protein

1

1

High-throughput

0.479

High

594305

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

8

Small-scale

0.479

High

706737

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

776300

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

4

High-throughput

0.479

High

776304

TFC5
Transcription factor TFIIIB component B''

1

1

High-throughput

0.479

High

776306

SEN1
Helicase SEN1

1

3

Small-scale

0.479

High

776308

RPC10
DNA-directed RNA polymerase III subunit RPC10

1

10

High-throughput

0.479

High

753001

XPOT
Exportin-T

1

3

High-throughput

0.464

High

382021

H4
Histone H4

1

0

High-throughput

0.458

High

745697

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

776296

SPP41
Protein SPP41

1

0

High-throughput

0.458

High

776299

PP4R3
Serine/threonine-protein phosphatase 4 regulatory subunit 3

1

0

High-throughput

0.458

High

776302

MAF1
Repressor of RNA polymerase III transcription MAF1

1

0

High-throughput

0.458

High

776309

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

776310

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

776298

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

736544

RIM1
Single-stranded DNA-binding protein RIM1, mitochondrial

1

0

High-throughput

0.282

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025