HitPredict

Interactor 1: RAD3 (P06839)
General transcription and DNA repair factor IIH helicase subunit XPD (TFIIH subunit XPD) (EC 3.6.4.12) (DNA repair helicase RAD3) (RNA polymerase II transcription factor B subunit RAD3) (TFB subunit RAD3)
Gene: RAD3

Interactor 2: MET18 (P40469)
DNA repair/transcription protein MET18/MMS19 (Methyl methanesulfonate-sensitivity protein 19)
Gene: MET18

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.718

Property	Details
Experiments	11805837, 11805826, 16429126, 28539047, 22678362
Identification Methods	anti tag coimmunoprecipitation, tandem affinity purification, affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 778 Sc			1 1032
+	Hs
		574170 ERCC2_HUMAN (1-732): 0: 961: 53.06		MMS19_HUMAN (23-1027): 0: 981: 23.41
+	Hs
		1303009 RTEL1_HUMAN (2-722): 0: 648: 23.49		MMS19_HUMAN (23-1027): 0: 981: 23.41
+	Dm
		1182746 Q7KVP9_DROME (1-755): 0: 983: 53.48		MMS19_DROME (19-1027): 8.58e-135: 432: 20.00
+	Hs
		1302975 FANCJ_HUMAN (2-62): 1.75e-15: 83.2: 34.43		MMS19_HUMAN (23-1027): 0: 981: 23.41