HitPredict

Interactor 1: LIPL (P06858)
Lipoprotein lipase (LPL) (EC 3.1.1.34) (Phospholipase A1) (EC 3.1.1.32)
Gene: LPL

Interactor 2: HDBP1 (Q8IV16)
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPI-HBP1) (GPI-anchored HDL-binding protein 1) (High density lipoprotein-binding protein 1)
Gene: GPIHBP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.90 0.785

The method score is based on:

Property Details
Experiments 30559189, 20124439
Identification Methods comigration in non denaturing gel electrophoresis, x-ray crystallography, x ray scattering, enzyme linked immunosorbent assay, affinity technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PLAT~UPAR_LY6
Common GO terms GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0019433 - triglyceride catabolic process
GO:0042632 - cholesterol homeostasis
GO:0070328 - triglyceride homeostasis
and 2 others

more...
Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024