HitPredict

Interactor 1: TY3H (P07101)
Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH)
Gene: TH

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23444366
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019904 - protein domain specific binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 528 Hs			1 245
+	Hs
		421378 TY3H_HUMAN (1-528): 0: 862: 100.00		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Rn
		378419 TY3H_RAT (1-527): 0: 796: 83.90		1433Z_RAT (1-245): 3.06e-142: 399: 80.00
+	Hs
		421377 TY3H_HUMAN (1-528): 0: 862: 100.00		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		570814 TPH1_HUMAN (114-527): 0: 671: 50.24		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		909787 TPH2_HUMAN (114-527): 0: 647: 50.71		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53